Scientist (mfd) in R&D Protein Chemistry
Share
Job Location:
Weilheim-Schongau - Germany
Monthly Salary:
Not Disclosed
Posted on:
10 hours ago
Vacancies:
1 Vacancy
Job Summary
At Roche you can show up as yourself embraced for the unique qualities you bring. Our culture encourages personal expression open dialogue and genuine connections where you are valued accepted and respected for who you are allowing you to thrive both personally and professionally. This is how we aim to prevent stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche where every voice matters.
The Position
In our Raw Material Development Protein Chemistry department you as a Scientist (m/f/d) in R&D Protein Chemistry will work at the crucial interface of research and production responsible for the research and development of protein-based raw materials for diagnostic tests (mainly for the Elecsys platform).
You will join an experienced versatile and open team specializing in the purification characterization and chemical as well as enzymatic functionalization of proteins. Together we are responsible for the development validation and transfer of manufacturing processes and analytical methods to our colleagues in production acting as a central service partner for protein-chemical and immunological analytics.
Your Key Responsibilities
You will develop optimize and validate production-ready and reproducible processes for the manufacturing and analysis of immunological reagents (e.g. highly specialized antibody and antigen conjugates) and take responsibility for their transfer to production for highly regulated in-vitro diagnostics (IVDs).
You will use state-of-the-art chromatographic methods as well as established biochemical physicochemical and immunological analytics for the purification and characterization of biological raw materials with a special focus on functional characterization in the Elecsys immunoassay.
You will assume technical responsibility for lab technicians act as a subject matter expert and consultant for project partners and actively contribute your experience to elevate the teams methodological know-how.
Other Responsibilities
Independent planning evaluation interpretation and documentation of experiments according to QM specifications.
Purification of antibodies or antigens from various sources (e.g. eukaryotic cell culture supernatants E. coli native human materials).
Supervision of raw material development projects according to valid guidelines (incl. planning coordination in the matrix and cost control).
Providing expert advice to project partners especially regarding reagent design and interference removal.
Studying and processing relevant scientific literature and patents.
This position requires the willingness to handle human materials.
Who you are
You hold a successfully completed PhD in Biochemistry Chemistry Biology Molecular Biotechnology or a related discipline. (Alternatively: a Masters degree (m/f/d) with several years of professional experience preferably with a protein chemistry background ).
You possess in-depth specialized knowledge in protein chemistry and biochemistry particularly in the purification modification and conjugation of proteins (chemical and/or site-directed conjugation methods).
You have sound experience in protein-analytical characterization (physicochemical biochemical immunological) and ideally knowledge of immunoassays and diagnostic platforms.
You are characterized by teamwork proactive communication and a structured independent approach to project management.
You are open to digitalization and communicate confidently in German and English (oral and written).
This position is temporary for 2 years.
Your Application
We make it easier for you: Please upload only your current and compelling resume and the certificate of your highest qualification.
We look forward to receiving your application!
Your contact to us! With people. For people.
Do you need further support
Key Skills
- Laboratory Experience
- Vendor Management
- Design Controls
- C/C++
- FDA Regulations
- Intellectual Property Law
- ISO 13485
- Research Experience
- SolidWorks
- Research & Development
- Internet Of Things
- Product Development
About Company
F. Hoffmann-La Roche AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel.
