Product Manager, Translational Research & Systems Biology, Disease Biology & PharmTox Product Line

Job Description

Location: NJ PA Boston/Cambridge

Job Description:

The Research and Development Sciences (RaDS) value team in our Companys R&D IT brings together product management engineering and data science expertise. We enable data technology and services that accelerate our scientists ability to discover and develop innovative medicines that change the course of human the RaDS value team the Product organization is responsible for implementing capabilities and associated services to advance the drug discovery and development pipeline. Our IT team operates as a business partner proposing ideas and innovative solutions that enable new organizational capabilities. We collaborate internationally to deliver the services and solutions that help everyone to be more productive and enable innovation.

We are seeking a motivated and talented Product Manager to join the RaDS Product organization. The position will report to the Lead of the Disease Biology and PharmTox Product Line. The ideal candidate will partner closely with key business stakeholders the product engineering data science and other IT teams to leverage advanced computational modeling and simulation tools to support pharmaceutical researchers in predicting drug behavior improving decision-making and accelerating the path to market. The goal of this product is to shorten the path from discovery to clinical proof-of-concept while reducing failure risk by making decisions based on mechanistic insight quantitative prediction and robust well-documented evidence. Applications in this area accelerate and de-risk translational research by providing predictive PK/PD/QSP modeling capabilities utilizing experimental data bioinformatics and clinical knowledge to de-risk candidates before first-in-human trials and enable clinical use of biomarkers.

Primary Responsibilities:

Partner closely with R&D scientists and Business Technology Partners to own set and communicate the product vision strategy and outcome roadmap aligned with strategic priorities.

Deeply understand user needs (scientists bioinformaticians data scientists lab operations) through interviews shadowing and usage analytics.

Map processes and information architecture to identify pain points and automation opportunities.

Define clear problem statements requirements and success metrics; author Product requirements document user stories and acceptance criteria

Drive solution discovery and rapid prototyping with cross-functional teams to evaluate value usability feasibility and business viability.

Prioritize features and trade-offs using impact effort and risk frameworks; manage backlog and release planning

Manage scientific applications and lead squads to build user-friendly scientific data and technology products; handle risk assessment and vendor engagement as needed.

Evaluate internal and external tools (e.g. predictive modeling simulation target discovery biomarker tracking); Manage vendor relationships to influence roadmaps and integrate with internal systems and the data lake.

Partner with product tech leads to ensure seamless integration across the ecosystem and upstream/downstream systems.

Apply industry standards and ontologies to develop FAIR (Findable Accessible Interoperable Reusable) applications advancing in silico models and AI/ML approaches for drug discovery.

Create and maintain documentation including SDLC deliverables (GxP and non-GxP) guidelines

SOPs training materials and user communications.

Support regulatory audits and inspections by collaborating with stakeholders and Quality units to provide documentation and respond to inquiries.

Coach teams to adopt a customer-centered product mindset; proactively remove roadblocks and escalate issues to maintain momentum.

Drive adoption using metrics and user feedback; analyze engagement create reports/visualizations and run user groups to inform continuous improvement.

Promote available capabilities to stakeholders fostering collaboration and integration across teams to avoid silos.

Develop a cohesive strategy to manage an orthogonal suite of products and applications maximizing impact while reducing costs and redundancy.

Diligently manage total cost of ownership

Monitor the competitive landscape standards and emerging technologies in scientific software and data platforms.

Use data-driven insights (synthesized from research observations and usage) to inform decisions and refine strategy.

Skill sets:

5 years of experience in scientific software development pharmaceutical sciences bioinformatics target discovery quantitative systems pharmacology model-based drug development (MBDD) or scientific data management.

Proven experience leading cross-functional teams to launch and manage software products; define user stories and ensure product development aligns with business requirements.

Good understanding of MBDD Pharmacokinetic/Pharmacodynamic modeling and pre-clinical development domain and processes.

Familiarity with bioinformatics pathway analysis tools and systems biology approaches used in scientific software.

Experience with scientific modeling tools and workflows (COTS in-house open source); ability to assess integrate and scale them

Solid grasp of SDLC and Agile practices; comfortable operating in GxP-regulated environments

Exceptional communicator who bridges science engineering and business; customer-centric and effective in a matrixed organization

Proficient with product and UX tooling (e.g. Jira Confluence Mural Figma Balsamiq); capable of producing clear documentation and visuals

Working knowledge of databases ontologies and data standards relevant to drug discovery; familiarity with information modeling (e.g. Visio)

Proven ability to work independently and asynchronously across time zones with excellent cross-cultural and organizational communication skills.

Highly organized detail-oriented and strong in time and project management; excellent written and verbal communication

Experience leading multidisciplinary squads to develop and onboard scientific applications and tools

Education Minimum Requirement:

Bachelors degree with 5 years of experience or masters with 3 years in a scientific or technical discipline such as biology pharmaceutical sciences bioinformatics computer science biostatistics biomedical engineering or chemistry.

Preferred Experience and Skills:

Experience as a scientist Informatics Analyst or IT analyst in a drug discovery or development environment specifically target discovery or quantitative systems pharmacology

Prior scientific programming experience

Proficiency with data analytics/mining tools (e.g. R Python Perl MATLAB)

Familiarity with relational databases (SQL Oracle PostgreSQL) and data integration.

Experience with informatics workflows pipeline development and knowledge graphs.

Knowledge of computational platforms including high-performance clusters and cloud computing environments.

Experience supervising and mentoring team members

Skill in data visualization and dashboards (e.g. Spotfire R Shiny Power BI) with the ability to craft compelling data narratives

Experience working in Agile development environments

Required Skills:

Preferred Skills:

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The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

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