Scientist LC-MS Bioanalytical

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist - LC-MS Bioanalytical

What you will do

Lets do this. Lets change the this vital role you will support the design development validation and implementation of robust LC-MS/MS bioanalytical methods for a wide range of therapeutic modalitiesincluding small molecules oligonucleotides proteins and other complex molecular entitiesto enable GLP preclinical and regulated clinical studies. Given the scope of projects the role will involve multidisciplinary interactions with scientists across research and development at Amgen. The position is lab-based and has significant emphasis on data management/fidelity report generation effective time management communication and data presentation.

• Perform quantitative bioanalytical experiments and organize data and results including planning and running LC-MS/MS bioanalysis and preparing and analyzing biological samples
• Develop and implement LC-MS/MS bioanalytical methods with quick turnaround times.
• Conduct small and large molecule bioanalysis in non-clinical and clinical samples from various matrices (plasma urine CSF tissues).
• Perform biological sample extraction using protein crash (PPT) SPE LLE and/or affinity capture methodologies.
• Generate complete accurate and concise documentation using electronic systems and laboratory notebook
• Ensure bioanalytical data meets regulatory expectations for global submissions by maintaining accurate records and staying current with industry guidelines.
• Author study reports standard operating procedures analytical methods memos and other regulatory-compliant documents.
• Communicate bioanalytical data to key discovery and development teams contribute to scientific publications and present at professional meetings.
• Comply with safety guidelines and site-specific procedures which include but is not limited to the completion of training on assigned tasks maintenance of training records laboratory documentation and following detailed SOPs and other written procedures.
• Perform general laboratory housekeeping activities and operational support as needed including QC of reports.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The vital attribute professional we seek is a type of person with these qualifications.

Basic Qualifications:

Doctorate degree PhD or PharmD or MD and relevant post-doc where applicable and 1-3 years of relevant industrial or postdoctoral experience

Or

Masters degree and 5 years of relevant industrial/technical experience

Or

Bachelors degree and 7 years of relevant industrial/technical experience

Preferred Qualifications:

• Prior experience in CRO or pharma/biotech strongly desired
• Strong technical expertise in quantitative mass spectrometry on triple quadrupole (QQQ) platforms as well as HRMS
• Experience with an array of analytical technologies that can accelerate bioanalysis inclusive of automation and/or micro-sampling
• Prior GLP and GCP experience.
• Demonstrated expertise in working with a variety of sample types (e.g. blood plasma serum tissues cerebrospinal fluid) and employing diverse sample preparation techniques (e.g. SPE LLE immunocapture) to support analysis of different therapeutic modalities including small and large molecules by LC-MS.
• Prior experience in bioanalytical (regulated) assay execution and transfer to CROs
• Must be willing to work in a fast-paced multi-project environment with high workload demands and consistently deliver high-quality results within established timelines.
• Demonstrated ability to resolve scientific challenges efficiently and prioritize effectively
• Excellent scientific problem-solving skills
• Excellent project and time management abilities
• Ability to work collaboratively with internal and external stakeholders
• Supervisory and mentoring experience in a lab-based setting

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models including remote and hybrid work arrangements where possible

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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