Thesis work, 30 credits Histological Signatures of AKI-to-CKD Transition
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Posted on:
11 hours ago
Vacancies:
1 Vacancy
Job Summary
Explore how kidneys progress from acute injury (AKI) to chronic disease (CKD) by mapping maladaptive repair inflammation cell death and fibrosis in established animal models. You will identify histological biomarkers and pathways that may guide targeted therapies and improve patient outcomes.
About AstraZeneca:
AstraZeneca is a global science-led patient-centered biopharmaceutical company focusing on discovering developing and commercializing prescription medicines for some of the worlds most serious diseases. But were more than a global leading pharmaceutical company. At AstraZeneca were dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.
About the Opportunity:
As a Thesis Worker at AstraZeneca youll find an environment thats full of unique opportunities and exciting challenges. Here youll have the opportunity to pursue your areas of interest whilst equally developing a broad skillset and knowledge base to get the best out of your experience. Youll be working on meaningful projects to make an impact and deliver real value for our patients and our business.
Thesis Work Description:
As a masters student you will investigate histological changes underlying the AKI to CKD transition with emphasis on cell death inflammatory and profibrotic processes. The project involves analyzing kidney tissue across defined injury and recovery timepoints from established animal models performing tissue processing and single/multiplex immunolabelling (IHC/IF) and acquiring advanced imaging using whole-slide scanning and fluorescence/confocal microscopy. You will quantify markers of maladaptive repair inflammation fibrosis and cell death assess their spatial distribution and co-localization. The work includes integrating findings into pathophysiological frameworks and delivering a thesis report with figures method SOPs and a dataset of validated histological markers with opportunities to contribute to internal presentations and potential publications.
You will be joining the Biosciences Technology Imaging Team which plays a crucial role in providing essential histology data for the Cardiovascular Renal and Metabolism (CVRM) disease areas. Our imaging group is at the scientific forefront utilizing the latest advancements in histology cutting-edge imaging techniques and sophisticated image analyses.
Structure:
- Duration: Spring term 2026
- Credits: 30
Essential Requirements:
- Enrolled in a Masters program in biomedical sciences molecular medicine pathology or related fields.
- Well-organized and focused mindset.
- Strong Problem-solving skills.
- Strong oral and written communication skills.
- Desire to learn and try new things.
So whats next
Apply today and take the chance to be part of making a difference making connections and gaining the tools and experience to open doors and fulfil your potential. We cant wait to hear from you!
We welcome your application as soon as possible but ahead of the scheduled closing date 23rd of November 2025. In the event that we identify suitable candidates ahead of the scheduled closing date we reserve the right to withdraw the vacancy earlier than published.
Date Posted
10-nov.-2025Closing Date
23-nov.-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.
Key Skills
- Photography
- Color Correction
- Shot List
- Adobe Photoshop
- Photo Shoots
- Youtube
- Camera Movement
- Cinematography
- Audio Equipment
- B-roll
- Camera Operation
- Final Cut Pro
- Digital Media
- Video production
- Web Series
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more
