Project Lead Biologics, Amplify
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Job Location:
Somerville, NJ - USA
Monthly Salary:
$ 144206 - 209757
Posted on:
08-11-2025
Vacancies:
1 Vacancy
Job Summary
Site: Mass General Brigham Incorporated
The Project Lead Biologics will act as the Chief Scientific Officer of their approved portfolio programs in a manner reminiscent of pre-seed/seeded new companies leveraging funding from Mass General Brigham. The Project Lead Biologics will participate and/or lead in the triage diligence planning and investment approval process for select portfolio programs prior to operating the approved programs. The Project Lead will also participate in commercialization activities including getting external feedback about prospective investments and pitching to prospective investors and partners. The Project Lead Biologics candidate will combine their expertise in biologics therapeutic development and particular domains such as early stage proof of concept through preclinical development as well as project leadership to operationalize and de-risk early stage academic investigator technologies. Candidates for this role will be highly motivated by the prospect of working on the forefront of life science innovation and advancing the healthcare mission of Mass General Brigham. The ideal candidate will also have participated in fundraising and early stage company science operations.
Duties and Responsibilities
- Leads assigned as well as invested projects in close collaboration with the Amplify leadership team physicians and researchers at the hospitals Innovation colleagues and industry representatives.
- The Project Lead Amplify will in effect perform as the principal of chief science/operational officer for their portfolio projects.
- Applies knowledge of biologic therapeutic product development to effectively diligence select scope plan/budget pitch and implement early innovative projects of their own as well as assist in other project triage and diligences as part of the Amplify team.
- Can readily assess commercial potential of assigned projects and assess the key risks to be mitigated.
- Has a working understanding of intellectual property filing and prosecution especially as it intersects with new company or partnership commercialization strategies.
- Effectively conducts direct and regular interactions with hospital-based investigators and stakeholders investors and industry collaborators external advisors contract vendors and consultants.
- Runs the day-to-day science operations of multiple projects in collaboration with Mass General Brigham researchers with oversight of external contract vendors and consultants engaged in activities that may include discovery to candidate nomination of biologic molecules safety studies product manufacturing development of clinical and regulatory plans and commercial analyses.
- Effective in designing product/program plans to individual experiments including analyzing and interpreting in vitro and in vivo datasets.
- Capable of developing and managing program budgets and engaging with finance and operations colleagues to oversee spending as well as inform commercialization plans.
- Ensures that deliverables associated with each project is completed on time within budget to meet or exceed targets set by Amplify.
- Capable of producing high quality written materials for project operations communications with stakeholders and pitches for project approval to internal and external investment committees.
- Thrives in working in close collaboration with colleagues working in diverse roles including other Amplify Leads MGB Ventures MGB academic Innovators BD & Licensing and other MGB Translational Program Managers.
- In addition to their Amplify responsibilities the Project Lead will also serve as an experienced advisory resource to Venture and Licensing colleagues as well as other Innovation colleagues engaged in translational development and initiatives for Mass General Brigham technologies.Hybrid399 Revolution Drive40RegularDay (United States of America)Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religious creed national origin sex age gender identity disability sexual orientation military service genetic information and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact Human Resources at .
Mass General Brigham relies on a wide range of professionals including doctors nurses business people tech experts researchers and systems analysts to advance our mission. As a not-for-profit we support patient care research teaching and community service striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The Project Lead Biologics is accountable for identifying investing in and leading technology projects and initiatives within the Amplify portfolio. Amplify is the translational accelerator that funds and operates projects from Mass General Brigham investigators that have very high commercial potential. The Project Lead will be a vital contributor to the success of Amplify in translating promising new idea to reality and creating value with these new technologies.The Project Lead Biologics will act as the Chief Scientific Officer of their approved portfolio programs in a manner reminiscent of pre-seed/seeded new companies leveraging funding from Mass General Brigham. The Project Lead Biologics will participate and/or lead in the triage diligence planning and investment approval process for select portfolio programs prior to operating the approved programs. The Project Lead will also participate in commercialization activities including getting external feedback about prospective investments and pitching to prospective investors and partners. The Project Lead Biologics candidate will combine their expertise in biologics therapeutic development and particular domains such as early stage proof of concept through preclinical development as well as project leadership to operationalize and de-risk early stage academic investigator technologies. Candidates for this role will be highly motivated by the prospect of working on the forefront of life science innovation and advancing the healthcare mission of Mass General Brigham. The ideal candidate will also have participated in fundraising and early stage company science operations.
Duties and Responsibilities
- Leads assigned as well as invested projects in close collaboration with the Amplify leadership team physicians and researchers at the hospitals Innovation colleagues and industry representatives.
- The Project Lead Amplify will in effect perform as the principal of chief science/operational officer for their portfolio projects.
- Applies knowledge of biologic therapeutic product development to effectively diligence select scope plan/budget pitch and implement early innovative projects of their own as well as assist in other project triage and diligences as part of the Amplify team.
- Can readily assess commercial potential of assigned projects and assess the key risks to be mitigated.
- Has a working understanding of intellectual property filing and prosecution especially as it intersects with new company or partnership commercialization strategies.
- Effectively conducts direct and regular interactions with hospital-based investigators and stakeholders investors and industry collaborators external advisors contract vendors and consultants.
- Runs the day-to-day science operations of multiple projects in collaboration with Mass General Brigham researchers with oversight of external contract vendors and consultants engaged in activities that may include discovery to candidate nomination of biologic molecules safety studies product manufacturing development of clinical and regulatory plans and commercial analyses.
- Effective in designing product/program plans to individual experiments including analyzing and interpreting in vitro and in vivo datasets.
- Capable of developing and managing program budgets and engaging with finance and operations colleagues to oversee spending as well as inform commercialization plans.
- Ensures that deliverables associated with each project is completed on time within budget to meet or exceed targets set by Amplify.
- Capable of producing high quality written materials for project operations communications with stakeholders and pitches for project approval to internal and external investment committees.
- Thrives in working in close collaboration with colleagues working in diverse roles including other Amplify Leads MGB Ventures MGB academic Innovators BD & Licensing and other MGB Translational Program Managers.
- In addition to their Amplify responsibilities the Project Lead will also serve as an experienced advisory resource to Venture and Licensing colleagues as well as other Innovation colleagues engaged in translational development and initiatives for Mass General Brigham technologies.
Qualifications
Education and Experience
- Advanced degree(s) in science/technology/engineering plus 5-10 years of increasing responsibility in project management
- Experience in industry-based drug product development environment of 10 years is
- Prior experience in diligencing technologies either internally at a company or as a consultant to companies or investors
- Experience in successfully fundraising and operating in a startup environment is a plus
- Expertise with product development of biologic therapeutics including antibodies ADCs enzymes recombinant fusion proteins vaccines
- Familiarity with technologies and platforms used to develop biologic therapeutics including immunization library screening in silico and structural design as well as production of research grade to GMP proteins plasmids and cell lines.
- Deep and demonstrated experience with immunology and/or cell biology
- Strong ability to connect fundamental target biology to drug mechanisms
- Extensive capability across a wide range of technologies in assay development
- Proficiency in Microsoft Office applications as well as project management tools
- Strong ability to manage competing complex deliverables and deadlines
- Demonstrates exceptional verbal writing presentation skills
- Established network of drug development contacts as well as investors is preferred
- Enthusiasm for working with exceptional and innovative researchers and technologies
- Specific expertise with biologic drug development of monoclonal antibodies recombinant enzymes and other proteins vaccines is essential
- Experience in overseeing IND-enabling activities including non-clinical pharmacology and CMC and advancing programs to the IND stage or beyond is beneficial.
Additional Job Details (if applicable)
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
$144206.40 - $209757.60/AnnualGrade
9EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham our competency framework defines what effective leadership looks like by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance make hiring decisions identify development needs mobilize employees across our system and establish a strong talent pipeline.
Required Experience:
Senior IC
Key Skills
- Administrative Skills
- Facilities Management
- Biotechnology
- Creative Production
- Design And Estimation
- Architecture
About Company
Patients at Mass General have access to a vast network of physicians, nearly all of whom are Harvard Medical School faculty and many of whom are leaders within their fields.
