Sr. Bioinformatics Software Engineer
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Job Location:
San Francisco, CA - USA
Monthly Salary:
Not Disclosed
Posted on:
7 days ago
Vacancies:
1 Vacancy
Job Summary
About Mithrl
We envision a world where novel drugs and therapies reach patients in months not years accelerating breakthroughs that save lives.
Mithrl is building the worlds first commercially available AI Co-Scientista discovery engine that empowers life science teams to go from messy biological data to novel insights in minutes. Scientists ask questions in natural language and Mithrl answers with real analysis novel targets and patent-ready reports. No coding. No waiting. No bioinformatics bottlenecks.
We are the fastest growing tech-bio startup in the Bay Area with over 12X YoY revenue growth. Our platform is already being used by teams at some of the largest biotechs and big pharma across three continents to accelerate and uncover breakthroughsfrom target discovery to mechanism of action.
Why This Role Matters
Were not just running pipelines. Were building systems that think like scientists. As a Senior Bioinformatician at Mithrl youll play a critical role in shaping how our AI platform understands and interprets complex genomics dataacross bulk RNA-seq single-cell CRISPR and beyond.
You wont just run tools youll know how they work. Youll help us design smarter algorithms build analysis frameworks that generalize and uncover insights that matter to drug discovery teams around the world. Youll work closely with our AI scientists software engineers and customer partners to bridge data computation and biology in real time.
What Youll Do
Ownership: Own the full bioinformatics stack -- from ingesting raw data to generating insights that drive real-world drug program decisions. Your work will be the scientific backbone of Mithrls AI.
Work closely with our product AI and customer teams to make sure your work is not just technically correct but biologically meaningful and decision-driving
Go beyond pipelines: Understand what tools are doing why results look the way they do and how to improve them
Collaborate with engineers and product teams to turn bioinformatics insights into scalable software features
Validate findings spot inconsistencies and suggest new hypotheses for customers and internal use
Translate messy biological questions into clean computational problems and vice versa
Mentor junior scientists and review technical outputs to ensure scientific accuracy
Stay up-to-date on the latest methods in transcriptomics functional genomics and statistical analysis
What Were Looking For
510 years of experience in bioinformatics
Deep fluency in Python and SQL including experience working directly with structured genomics data at scale
Strong grasp of statistical and machine learning methods applied to high-throughput biological data
Hands-on experience with modern genomics tools and file formats (e.g. GWAS aligners etc.)
Ability to interpret and debug pipeline results; not just run them
Strong scientific judgment clarity in communication and attention to detail
**Curiosity persistence and a drive to understand how things work
**High energy strong work ethic and a track record of getting things done
**Discipline Wins: At Mithrl the social currency is hard work and consistency. The problems were solving are complex and take time to bear fruit. We value teammates who show up every day work with focus and bring long-term discipline to their craft
Bonus: Experience working with AI/ML scientists or integrating bioinformatics with production software
What Youll Love
Scope: Shape how a cutting-edge AI platform thinks about biology and delivers real insight
Impact: Your work will directly influence drug discovery decisions at top biotech companies
Team: Join a world-class crew of AI scientists engineers and biologists working together at full speed
Culture: No ego no bureaucracy. Just deep thinking fast execution and high ownership
Location: Beautiful SF office with a focus on in-person high-bandwidth collaboration
Benefits: Comprehensive PPO health coverage through Anthem (medical dental and vision) 401(k) with top-tier plans
Required Experience:
Senior IC
Key Skills
- Spring
- .NET
- C/C++
- Go
- React
- OOP
- C#
- Data Structures
- JavaScript
- Software Development
- Java
- Distributed Systems
