Scientist, Protein Analytics, Discovery Biologics

Job Description

Early Biologics Characterization- Protein Analytics group is seeking a highly motivated scientist with experience in a biopharmaceutical setting. The selected individual will join the Discovery Biologics group at our Company and will have exceptional organizational and interpersonal skills along with a solid background in life sciences. The successful candidate will play a key role in the characterization of protein-based therapeutics supporting discovery and early development programs. This individual will be responsible for developing and applying state-of-the-art analytical techniques to assess protein identity purity structure and stability such as SEC HIC CE-SDS DSF DLS Buffer Exchange. The candidate will be expected to interface with other functional groups including in vitro display molecular biology and protein engineer functions. Good communication skills and the ability to present scientific data to multi-functional teams are critical.

This role will require an eagerness to learn and an ability to work with different teams and different equipment to operate a robust characterization platform. Your efforts will be a complement and core resource to existing capabilities and will serve to expand the teams ability to interrogate biologics diversity to identify optimal leads. You will have the opportunity to apply your enthusiasm and technical skills as a member of Discovery Biologics - Boston to support and help drive multidisciplinary biotherapeutic discovery programs. This is a full-time on-site position.

Responsibilities

• Contribute to our Companys Discovery Biologics pipeline by generating high quality data for protein characterization including antigens antibodies and other fusions proteins.

• Perform routine and advanced protein characterization using techniques such as: HPLC/UPLC (SEC IEX RP) Capillary electrophoresis (CE-SDS cIEF) LC-MS

• Interpret and present analytical data to cross-functional teams.

• Collaborate closely with protein engineering purification and formulation teams to support candidate selection and optimization.

• Follow and author technical reports SOPs and contribute to regulatory documentation as needed.

• Maintain accurate and organized laboratory records in compliance with internal quality standards.

• Serve as a functional area representative on program teams

• Promote the external reputation of our companys Discovery Biologics organization

• Generate frequent characterization summary reports.

• Troubleshoot automation methods and devices to maintain optimal high throughput protein analyses

Qualifications and Experience:

• A minimum of a B.S./ in a relevant field (e.g. protein sciences biophysics chemical or bioengineering biochemistry or related life sciences field) with additional training of 2 years of hands-on industry experience or Masters in Biochemistry or related discipline with 0-1 years of experience

• Hands-on experience with protein analytical techniques especially chromatography-based methods

• Familiarity with protein structure post-translational modifications glycosylation

• Excellent problem-solving skills and ability to work independently and collaboratively in a fast-paced environment

Required skills:

• Familiarity with biophysical techniques (SEC; HIC DSF DSC etc.) and their inherent data management

• Familiarity with LC-MS workflows and sample preparation

• Ability to multitask time management and prioritize activities.

• Excellent attention to detail and record keeping in electronic lab notebooks

• Excellent communication and collaboration skills

Preferred skills:

• Experience in other characterization workflows such as binding (SPR) or functional (cell based) assays

• Experience with EMPOWER is a plus

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As an Equal Employment Opportunity Employer we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race color age religion sex sexual orientation gender identity national origin protected veteran status disability status or other applicable legally protected a federal contractor we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences perspectives skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas broad experiences backgrounds and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively.

Learn more about your rights including under California Colorado and other US State Acts

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Effective September 5 2023 employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week Monday - Thursday although the specific days may vary by site or organization with Friday designated as a remote-working day unless business critical tasks require an on-site Hybrid work model does not apply to and daily in-person attendance is required for field-based positions; facility-based manufacturing-based or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.

The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

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