Scientist II, Radiochemistry (preclinical)

Needham, MA - USA

Monthly Salary: $ 63588 - 118093

Posted on: 10 hours ago

Vacancies: 1 Vacancy

Job Summary

What can we offer you

Apart from job satisfaction we can offer you:

HEALTH

Medical Dental and Vision benefits for you and your family including Flexible Spending Accounts (FSA)

YOURSELF

Paid time off policy including holidays and sick time
Internal growth and development programs & trainings

WEALTH

401(k) program life & accident insurance and disability insurance

This role offers scientific expertise in reviewing analyzing and resolving challenges within the radiolabeling process. Responsibilities include the design and hands-on execution of synthesis purification and formulation of radiotracers for use in in vivo imaging biodistribution and efficacy studies. The scientist will collaborate closely with cross-functional teams and manage multiple studies simultaneously to support preclinical nuclear medicine programs.
Key responsibilities include working safely and compliantly with radioactive materials and operating essential lab equipment such as HPLC and Radio-TLC.

Key Responsibilities:

Execute and manage the production of radiotracers used in PET/SPECT imaging and therapeutic research studies.
Develop and validate:
- Contribute to the design development and optimization of radio labeled compounds targeting complex biological markers for application in PET/SPECT imaging and therapeutic studies.
- Synthesis of novel PET/SPECT and therapeutic radiopharmaceuticals
- Purification methods for small and large molecules
- Analytical methods for HPLC and TLC
- Release criteria for imaging studies
- Dose formulation processes
Operate and maintain analytical and automated radiochemistry synthesis units.
Stay current on advancements in radiochemistry and imaging through literature review and attendance at scientific conferences.
Maintain clear accurate and up-to-date records.
Analyze data recognize aberrant results and propose corrective actions or next steps
Summarize data for reports papers and presentations.
Manage multiple projects simultaneously and prioritize tasks effectively
Mentor and guide junior team members.
Provide scientific expertise and troubleshooting internally and in communication with Sponsors related to radiochemistry.
Perform other duties as assigned.

Functional Competencies (Technical knowledge/Skills)

Experience with small and large molecule radiochemistry labeling purification and formulation
Working knowledge and experience with HPLC and TLC techniques in radiochemistry
Experience in conjugation with chelators and labeling with radiometals is preferred.
Prior experience with F-18 radiochemistry and radioiodination methods is considered advantageous.
An effective team player with the ability to collaborate across various departments
Ability to multi-task different projects and manage time effectively
Strong written and verbal communication skills that can reach an audience of varying levels of expertise

Experience Education and Certifications

Ph.D. in Chemistry or relevant field with 3 years or M.S. with 5 years of experience in an academic or pharmaceutical lab
Experience working with radioactive materials in a safe and compliant manner
Ability to lift more than 40 pounds
Proficient with Microsoft office
English: Fluent

This role is based in the Perceptive office/lab located in Needham MA. The annual base salary range for this role is $63588-$118093. This range represents the anticipated initial annual salary and may vary depending on several factors including the candidates experience and skills and may be subject to market rate adjustment.

Required Experience:

What can we offer youApart from job satisfaction we can offer you:HEALTHMedical Dental and Vision benefits for you and your family including Flexible Spending Accounts (FSA)YOURSELFPaid time off policy including holidays and sick timeInternal growth and development programs & trainingsWEALTH401(k) p...