Senior Associate Scientist ADC Chemistry
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Job Location:
Bothell, WA - USA
Monthly Salary:
$ 66500 - 110900
Posted on:
25-10-2025
Vacancies:
1 Vacancy
Job Summary
POSITION SUMMARY
The ADC (Antibody Drug Conjugate) Chemistry team discovers and advances novel ADC linker and payload technologies for targeted cancer therapies. This is a lab-based role that will support novel ADC technology development. You will participate in research projects involving the design and synthesis of novel ADC payloads and linkers. Your role may also include coordinating or performing biological assays to understand linker payload and ADC properties.
KEY RESPONSIBILITIES
- Design and perform multi-step syntheses of novel ADC payloads linkers and key intermediates.
- Work with minimal guidance to develop troubleshoot and optimize synthetic routes including modular routes for rapid analog generation and efficient scalable routes for early-stage drug candidates.
- Operate a variety of analytical instruments and technologies including HPLC LC/MS NMR to enable structural determination and purity assessment.
- Work effectively in both independent and highly collaborative settings.
- Analyze and accurately record data using Electronic Laboratory Notebooks.
- Actively participate in discussions and present results in the form of written reports and oral presentations.
- Adhere to all company safety scientific record keeping and compliance requirements.
MINIMUM QUALIFICATIONS
- Masters degree in synthetic organic chemistry experience or related discipline
- Bachelors degree with at least 3 years of industry synthetic organic chemistry experience
- Deep understanding of organic functional groups reaction mechanisms and reactivity.
- Experience using chemistry and literature/patent searching software to plan and execute synthetic strategies.
- Experience as a synthetic organic chemist familiar with a wide range of reaction types and having demonstrated multi-step synthesis purification and characterization of organic compounds especially using NMR and mass spectroscopy.
- Strong interpersonal skills and effective written/verbal communication.
- Experience working effectively in multi-disciplinary teams learning new skills and proactively solving problems
PHYSICAL/MENTAL REQUIREMENTS
Lifting sitting standing walking bending ability to perform mathematical calculations and ability to perform complex data analysis.
Relocation support availableWork Location Assignment:On Premise
The annual base salary for this position ranges from $66500.00 to $110900.00. In addition this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution paid vacation holiday and personal days paid caregiver/parental and medical leave and health benefits to include medical prescription drug dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits (). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name address and the type of payments or other value received generally for public disclosure. Subject to further legal review and statutory or regulatory clarification which Pfizer intends to pursue reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse your name address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Required Experience:
Senior IC
Key Skills
- Laboratory Experience
- ELISA
- Immunoassays
- Transfection
- Mammalian Cell Culture
- Suspension Experience
- Biochemistry
- Assays
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
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