Bioinformatics Engineer

Site: The Brigham and Womens Hospital Inc.

Mass General Brigham relies on a wide range of professionals including doctors nurses business people tech experts researchers and systems analysts to advance our mission. As a not-for-profit we support patient care research teaching and community service striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

We are seeking a motivated Bioinformatics Engineer to join Brigham and Womens Hospital. The ideal candidate will have experience working with large complex datasets transforming them into analysis-ready formats and leveraging high-performance computing for machine learning and statistical modeling. This role focuses on developing scalable pipelines to process real-world electronic health records (EHR) and clinical data enabling data-driven discovery in collaboration with clinical and research teamswith the ultimate goal of advancing diagnostic technologies for low- and middle-income countries. This position is an excellent opportunity for someone with strong data analysis or computational experience who is eager to apply those skills to cutting-edge biological and clinical research.

Data Engineering & Analysis
Design and implement pipelines for processing large-scale electronic health records and clinical datasets
Develop automated data cleaning validation and quality control workflows
Build scalable data processing systems capable of handling multi-million record datasets
Create and maintain data transformation scripts for standardizing clinical data formats
Collaborate with clinical scientists to translate research questions into analytical workflows
Ensure all data processing activities comply with HIPAA IRB protocols and institutional data governance policies
Machine Learning & AI Implementation
Develop and deploy machine learning models for clinical prediction and classification tasks
Implement feature engineering strategies specific to clinical and biomedical data
Build model validation frameworks appropriate for healthcare applications
Create automated model monitoring and performance evaluation systems
Stay current with ML/AI best practices in healthcare and regulatory requirements

This position involves working with sensitive patient data in secure computing environments. The role requires collaboration with clinical researchers IT teams and regulatory compliance officers. Some projects may involve tight deadlines related to clinical studies or regulatory submissions.

Education

Bachelors Masters or PhD in Bioinformatics Computer Science Bioengineering Statistics Mathematics or a related quantitative field

Can this role accept experience in lieu of a degree
Yes

Experience

Experience in bioinformatics engineering or other software engineering 1-2 years required

Experience with large-scale data processing and analysis

Understanding of statistical methods and experimental design principles

Proficiency in Python for data transformation analysis and visualization

Experience with distributed parallel or cloud computing environments

Familiarity with machine learning tools (scikit-learn PyTorch or TensorFlow)

Knowledge Skills and Abilities

- Strong interpersonal skills and ability to effectively interact with all levels of staff and external contacts.

-Solid analytical organization and time management skills.

-Strong analytical and problem-solving skills

-Excellent communication and documentation habits

-Ability to work independently and collaboratively across multidisciplinary teams

-Familiarity with cloud-based and containerized computing environments

-Knowledge of HIPAA compliance PHI handling and secure data environments

-Understanding of EHR data structures and clinical coding systems (ICD-10 LOINC etc.)

-Experience with workflow management systems

-Experience with data governance and reproducibility best practices

-Commitment to data integrity security and reproducible research-Back-end and API development using programs such as Python NodeJS C# Java R and/or Perl.
- SQL proficiency.
- Web development using programs such as Angular 6 and Python Flask.
- Familiarity with SDLC principles.

Onsite

60 Fenwood Road

40

Regular

Day (United States of America)

Pay Range

$73798.40 - $107400.80/Annual

Grade

6

At Mass General Brigham we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive and any offer extended will take into account your skills relevant experience if applicable education certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however it does not encompass all elements contributing to your total compensation addition to competitive base pay we offer comprehensive benefits career advancement opportunities differentials premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

The Brigham and Womens Hospital Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religious creed national origin sex age gender identity disability sexual orientation military service genetic information and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact Human Resources at .

Mass General Brigham Competency Framework