The Stevens lab applies cutting-edge methods in human tissues and human-relevant models to understand how interactions between the brains immune cells glia and neurons influence the development and dysfunction of synapses and circuits. We center our work on assessment of gene expression and cellular function in human tissue samples both from the brain and from peripheral immune compartments like the CSF and blood. Through the lens of human biology we are able to better understand the fundamental biology and etiology of diseases that are uniquely found in human beings. Our lab collaborates closely across the neurobiology genetics and therapeutics groups at the Stanley Center for Psychiatric Research as well as with many labs across Boston the U.S. and abroad. A successful candidate in this role will contribute to multiple projects supporting the overall goals of the lab and the Program: to improve brain health through groundbreaking basic and translational research.
Candidates should possess a bachelors degree in biology or a related field and at least four years of wet-lab research experience (or MS and 2 years of experience). Relevant knowledge and skills include preparation and staining of human tissue; immunohistochemistry; RNAscope; fluorescent confocal microscopy and image analysis; flow cytometry; and basic molecular biology methods (e.g. PCR DNA/RNA/protein purification cloning Western blotting).
Attention to detail careful note-keeping and experience developing modifying and troubleshooting experimental protocols are critical as is clear and open communication with colleagues both within and outside the lab.
The Stevens lab and the Broad Institute provide an outstanding environment for career development through formal scientific and leadership training programs informal mentorship opportunities and exposure to diverse cutting-edge science and scientists. Our ideal candidate is seeking a longer-term position in which to grow and develop as a scientist and team leader.
Day-to-day responsibilities Work with team members and collaborators to design and execute experiments essential to the groups collective success Work with project manager and lab manager to obtain manage and properly store human tissue samples Section tissues perform immunohistochemical staining RNAscope and other tissue analysis techniques Perform confocal light sheet and light microscopy imaging of tissue samples Quantitatively assess tissue features such as cellular morphology synapse number subcellular features or frequency of expression of a marker Document experiments and generate detailed reports in the form of figures graphs and slide decks Consult the literature supervisor and scientific staff to research try troubleshoot and optimize new methods that may be relevant to our projects Liaise with Broad platforms and programs (CDoT GP/BCL STP) for access to methods and equipment enabling high-throughput assays Attend and present data at team meetings and be an active contributor to lab discussions and collaborations
Requirements Bachelors of science degree in cell or molecular biology neuroscience or a related field plus four years of relevant lab experience (or Masters degree and two years experience) Excellent communication organization and time management skills A high level of initiative and motivation Ability to work both independently and with a team Ability to think creatively to solve problems and to know when to ask for help
Curiosity to learn new things and a passion to make a difference in the lives of patients by advancing the science of psychiatric and neurodegenerative diseases
The expected base salary range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to relevant skills experience education qualifications and other factors permissible by law.
At Broad your base pay is just one part of a comprehensive total rewards package. From day one this role offers a competitive benefits package including medical dental vision life and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race national origin religion age color sex disability protected veteran status or any other characteristic protected by local state or federal laws rules or regulations.
Should you need a reasonable accommodation to complete the application or interview process please contact for assistance.
The Stevens lab applies cutting-edge methods in human tissues and human-relevant models to understand how interactions between the brains immune cells glia and neurons influence the development and dysfunction of synapses and circuits. We center our work on assessment of gene expression and cellular function in human tissue samples both from the brain and from peripheral immune compartments like the CSF and blood. Through the lens of human biology we are able to better understand the fundamental biology and etiology of diseases that are uniquely found in human beings. Our lab collaborates closely across the neurobiology genetics and therapeutics groups at the Stanley Center for Psychiatric Research as well as with many labs across Boston the U.S. and abroad. A successful candidate in this role will contribute to multiple projects supporting the overall goals of the lab and the Program: to improve brain health through groundbreaking basic and translational research.
Candidates should possess a bachelors degree in biology or a related field and at least four years of wet-lab research experience (or MS and 2 years of experience). Relevant knowledge and skills include preparation and staining of human tissue; immunohistochemistry; RNAscope; fluorescent confocal microscopy and image analysis; flow cytometry; and basic molecular biology methods (e.g. PCR DNA/RNA/protein purification cloning Western blotting).
Attention to detail careful note-keeping and experience developing modifying and troubleshooting experimental protocols are critical as is clear and open communication with colleagues both within and outside the lab.
The Stevens lab and the Broad Institute provide an outstanding environment for career development through formal scientific and leadership training programs informal mentorship opportunities and exposure to diverse cutting-edge science and scientists. Our ideal candidate is seeking a longer-term position in which to grow and develop as a scientist and team leader.
Day-to-day responsibilities Work with team members and collaborators to design and execute experiments essential to the groups collective success Work with project manager and lab manager to obtain manage and properly store human tissue samples Section tissues perform immunohistochemical staining RNAscope and other tissue analysis techniques Perform confocal light sheet and light microscopy imaging of tissue samples Quantitatively assess tissue features such as cellular morphology synapse number subcellular features or frequency of expression of a marker Document experiments and generate detailed reports in the form of figures graphs and slide decks Consult the literature supervisor and scientific staff to research try troubleshoot and optimize new methods that may be relevant to our projects Liaise with Broad platforms and programs (CDoT GP/BCL STP) for access to methods and equipment enabling high-throughput assays Attend and present data at team meetings and be an active contributor to lab discussions and collaborations
Requirements Bachelors of science degree in cell or molecular biology neuroscience or a related field plus four years of relevant lab experience (or Masters degree and two years experience) Excellent communication organization and time management skills A high level of initiative and motivation Ability to work both independently and with a team Ability to think creatively to solve problems and to know when to ask for help
Curiosity to learn new things and a passion to make a difference in the lives of patients by advancing the science of psychiatric and neurodegenerative diseases
The expected base salary range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to relevant skills experience education qualifications and other factors permissible by law.
At Broad your base pay is just one part of a comprehensive total rewards package. From day one this role offers a competitive benefits package including medical dental vision life and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race national origin religion age color sex disability protected veteran status or any other characteristic protected by local state or federal laws rules or regulations.
Should you need a reasonable accommodation to complete the application or interview process please contact for assistance.