iPSC Core Manager
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Job Location:
Berkeley, CA - USA
Monthly Salary:
Not Disclosed
Posted on:
16-10-2025
Vacancies:
1 Vacancy
Job Summary
Experience level: PhD or equivalent work experience.
The position
We are seeking a motivated independent and highly organized iPSC Scientist to own and scale our iPSC core. You will play a central role in building the foundation of Conceptions preclinical and later manufacturing arm for CMC readiness.
This is a high-ownership high-growth role that starts heavily in the lablearning systems people and protocolsand grows into leading a large core spanning multiple iPSC lines and differentiation protocols. You will establish stability traceability and consistency across our iPSC operations implementing strong QC guidelines and standard practices.
Over time you will expand the core to manage multiple iPSC lines and differentiation protocols build predictive QC systems (ML imaging sequencing) and prepare workflows for preclinical and translational work.
Our mission
Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs). Our mission is to unlock new possibilities for fertility reproductive health and genetic diversity. We are building a world-class team at the intersection of stem cell biology developmental biology and synthetic biology to make this vision a reality.
What youll do
Organize and run the iPSC core day-to-day
Maintain cell banks and execute QC for iPSCs and feeder lines
Track QC results reagents lots consumables and equipment; manage incubators and hoods in collaboration with Operations
Work closely with Operations to ensure differentiation protocols remain extremely stable and repeatable
Build and document SOPs for routine workflows
Collaborate with the Cell Engineering team to validate QC bank and integrate new cell lines into the core
Establish strong communication loops with R&D teams to manage cell handoffs define acceptance criteria and communicate disruptions or delays to maintain quality
Team Leadership
Lead mentor and grow a small team; set expectations for consistency documentation and accountability
Keep junior scientists engaged and motivated on core work; invest in training and mentorship
Coordinate across R&D and Operations to communicate timings risks delays and mitigations proactively
R&D and QC Innovation
Collaborate with R&D scientists to standardize and scale directed differentiation of at least one lineage expanding to multiple lines over time
Partner with ML and computational biology experts to explore automated imaging and RNAseq as predictors of long-term culture success
Develop and implement new QC methods for differentiations
Propose innovations to improve cell quality efficiency and early risk detection
What were looking for
PhD in Cell or Developmental Biology or related field (preferred) or Masters with relevant industry experience
Extensive senior-scientist-level experience with iPSC culture and differentiation protocols to one or more lineages
Proven ability to run organized traceable high-quality cell culture operations
Experience mentoring or managing junior scientists
Exceptionally organized detail-oriented and proactive
Strong communicator and collaborator
Motivation to build systems that scale from R&D to preclinical and CMC readiness
Why join us
Impact: Define and accelerate one of Conceptions most critical programs with the potential to transform human reproduction.
Ownership: Operate with autonomy inside a growing biotech company.
Growth: Build and lead a team from the ground up.
Mission-driven: Work alongside passionate scientists tackling one of the most exciting frontiers in biology with a deeply aligned team.
We are well funded and well connected in Silicon Valley. We offer competitive pay company equity and excellent healthcare benefits for these positions.
To learn more about the original mouse proof of concept to live birth that inspired us see Experience:
Manager
Key Skills
- Restaurant Experience
- Customer Service
- Employee Evaluation
- Management Experience
- Math
- Employment & Labor Law
- Sanitation
- Leadership Experience
- P&L Management
- Mentoring
- Supervising Experience
- Restaurant Management
About Company
First published in 1869, Nature is the world’s leading multidisciplinary science journal. Nature publishes the finest peer-reviewed research that drives ground-breaking discovery, and is read by thought-leaders and decision-makers around the world.
