Specialist, Engineering Microbial Process Operations (Onsite)

Job Description

The Microbial Process Operations (MPO) Team is seeking a Specialist to support operations for enzyme process development and characterization. Our team is part of Continuous & Expression Technologies (CET) within the Process Research & Development Enabling Technologies (PR&D ET) group focused on advancing technologies for the manufacturing of diverse biomolecules including novel biotherapeutics vaccines and engineered enzymes. The Specialist will execute scientific and operational activities to support the development of robust scalable and compliant microbial processes.

The chosen candidate should possess strong interpersonal communication and collaboration skills and should embrace and model our core values of diversity equity and inclusion and foster a supportive culture where all employees can thrive.

Responsibilities include but are not limited to:

• Execute and analyze fermentation experiments at multiple scales (e.g. mini bioreactors benchtop bioreactors pilot scale) ensuring high-quality reproducible results.

• Perform downstream processing operations to ensure efficient enzyme recovery and purification delivering enzyme powders that meet quality and yield specifications.

• Maintain timely accurate and comprehensive documentation of all experimental work and process data in compliance with company standards.

• Troubleshoot routine issues related to bioreactor and downstream process operations to ensure consistent reliable and robust operations; escalate and collaborate on more complex issues with senior team members.

• Contribute to process improvement initiatives aimed at improving process efficiency reproducibility and scalability.

• Support implementation and maintenance of automation data pipelines and process analytical technologies.

• Follow and promote laboratory safety compliance and operational best practices supporting a culture of operational excellence and continuous improvement.

• Collaborate with cross-functional teams to support technology transfer and scale-up activities.

Education Minimum Requirement:

• Masters degree with at least 1 year of relevant industry experience or

• Bachelors degree with 2 years of relevant industry experience in chemical engineering bioengineering biological sciences or related fields.

Requirements:

• Working knowledge of aseptic techniques and fermentation process control strategies for batch and fed-batch processes.

• Experience operating and troubleshooting automated bioreactors at various scales including mini bioreactors bench scale or pilot scale systems; ability to follow established SOPs and escalate equipment and process issues appropriately.

• Understanding of common analytical technologies for biomass metabolite measurement and off-gas analysis.

• Solid organizational documentation and problem-solving skills with a strong commitment to maintaining rigorous safety and quality standards.

• Ability to work effectively within cross-functional teams building working relationships across the department.

Preferred Experience and Skills:

• Hands-on experience with ambr250 bench-scale or pilot scale bioreactors.

• Understanding of microbial strain development and genetic engineering techniques to support process optimization.

• Familiarity with downstream unit operations and basic protein purification concepts sufficient to perform routine operations and sample handling.

• Experience with design of experiments data analysis and data visualization tools to support process optimization.

• Experience supporting tech transfer or scale-up activities from R&D to pilot scale.

• Experience working in a regulated environment (e.g. cGMP) supporting biopharmaceutical or enzyme manufacturing processes.

To learn more about the PRD team click: Join Our Process Research & Development Team.

PRD

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Effective September 5 2023 employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week Monday - Thursday although the specific days may vary by site or organization with Friday designated as a remote-working day unless business critical tasks require an on-site Hybrid work model does not apply to and daily in-person attendance is required for field-based positions; facility-based manufacturing-based or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note this Hybrid work model guidance also does not apply to roles that have been designated as remote.

The salary range for this role is

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

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