Co-op, Biology Drug Discovery

Co-op Biology Drug Discovery

Address:

45 Sidney Street

Cambridge MA 02139

Blueprint Medicines a Sanofi company is a global biopharmaceutical company that invents life-changing medicines. We seek to improve and extend patients lives by solving important medical problems with a focus on allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a track record of success with two approved medicines including AYVAKIT/AYVAKYT (avapritinib) which we are bringing to patients with SM in the U.S. and Europe. Leveraging our established research development and commercial capability and infrastructure we aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases and solid tumors.

Responsibilities:

We are seeking a motivated graduate-level co-op student interested in contributing to our drug discovery programs with a focus target validation and assay development for testing candidate drug compounds. This student will apply advanced molecular biology techniques to evaluate candidate compounds and contribute to the scientific direction of our programs.

Projects will be crafted along one or multiple of the following key areas based on interest and business needs:

Lab Work:

• Design execute and analyze in vitro cellular assays across a variety of cell lines to assess drug efficacy and biological impact
• Perform mechanism of action studies on human and engineered cell lines including proliferation assays signaling assays protein-protein interactions and high content imaging assays
• Maintain cell cultures generate stable cell lines using RNA interference (RNAi) or gene editing techniques (CRISPR/Cas-9)
• Execute drug combination studies on cell lines of interest to evaluate synergistic or antagonistic effects.

Data Analysis and Documentation:

• Analyze experimental data using GraphPad Prism Excel and other relevant tools
• Maintain accurate and detailed electronic laboratory notebooks in compliance with Blueprint Medicines standards

Collaboration and Communication:

• Participate in regular team meetings present findings and contribute to scientific discussions
• Collaborate with cross-functional teams seek feedback and actively contribute to a culture of innovation
• Perform other duties as assigned.

ONSITE EXPECTATIONS: This is a lab-based position and the Co-op is expected to work onsite 5 days/week.

Qualifications:

• Currently enrolled student pursuing a PhD or masters program in biomedical sciences molecular biology or related field
• 1-2 years of independent laboratory research
• Strong foundation in cellular and molecular biology
• Proficiency in core lab techniques (e.g. tissue culture Western blotting DNA/RNA extraction immunofluorescence cell proliferation and viability assays experience generating cell lines a plus)

What additional qualifications will make you a stronger candidate

• Strong commitment to pursuing a career in research
• Excellent communication organizational and analytical skills
• Commitment to our Core Values: Patients First Thoughtfulness Urgency Trust Optimism

Our Co-op Program:

Blueprints Co-op program is 6 months long. The program is designed to provide students with deep functional expertise within their department and a broad understanding of the life sciences -ops are paired with dedicated mentors for personalized learning and career development guidance. The program includes lunch and learn sessions networking events a student volunteer day and other networking opportunities. It culminates in a final poster presentation where interns showcase their work.

Dress Code: Blueprints offices are a business casual environment. Business casual means attire that is professional but also relaxed such as slacks or business dress pants skirts/dresses khakis chinos or dark jeans without holes paired with button-down shirts sweaters blouses or polo shirts and closed-toed shoes. It typically excludes formal suits or very casual clothing such as athletic wear or flip flops.

Spring 2026 Co-op Program Dates: Monday January 5^th Friday June 26^th

Pay Range: Our Co-ops are paid hourly based on previous Co-op experience. The expected pay range for this role is $32.00 - $35.00per hour.

Who will my employer be

You will be employed by Magnit LLC for all purposes and not Blueprint Medicines a Sanofi Company. As your employer Magnit will assign you to provide services to Blueprint as a co-op or intern. Under this arrangement co-ops and interns will have the opportunity to learn about Blueprint Medicines a Sanofi Company and gain meaningful hands-on experience. Please note: Co-op and interns are not employees of Blueprint in any way and do not qualify for participation in Blueprints benefit plans.

Equity Diversity Inclusion and Affirmative Action

To do our best work we need different viewpoints. Therefore we celebrate diversity and embrace inclusion. As an equal opportunity employer we are dedicated to building a team that represents a variety of backgrounds perspectives and skills. We strive to ensure that we maintain a positive and enriching work environment for all. For more information on Magnits privacy notice click on privacy notice.

Magnit LLC recognizes the importance of individually held beliefs re: appropriate dress/attire and will reasonably accommodate an employees religious beliefs unless the accommodation creates an undue hardship. Those requesting attire accommodation based on religious beliefs should reach out to their Magnit representative.

Magnit is a Global industry leader with one simple goal of shaping and delivering the next chapter in workforce management for our employees clients suppliers and partners around the world.

Why Blueprint

At Blueprint Medicines a Sanofi Company we achieve impactful results because of our global crew of compassionate innovators the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights which drives our success.