Scientist, Clinical Biomarker Laboratory, Flow Cytometry

The Role:

Moderna is seeking a motivated and skilled Scientist to join the Clinical Flow Cytometry group. This individual will serve as the Cytometer Instrument Lead while also executing clinical testing assay/panel development and validation activities under GCLP guidelines. The Scientist will work with a team of scientists to deliver high-quality biomarker data to support clinical programs across multiple therapeutic areas.

The successful candidate will have strong technical expertise in spectral flow cytometry instrumentation (Cytek Aurora) along with experience in developing validating and executing flow cytometrybased assays. This role requires deep understanding of immunology experience in clinical laboratory environments and the ability to apply best practices in translational and clinical sample testing. You will be an integral part in applying high parameter flow and complex assays to generate key clinical data to drive clinical trial decisions.

Heres What Youll Do:

• Serve as an internal technical expert (Instrument Lead) for flow cytometry instrumentation operation and maintenance.

• Ensure all cytometers are harmonized to generate equivalent data remain ready for clinical acquisition adhere to stringent QC program and that all documentation meets GCLP Compliance needs and is available in the event of internal or external audit.

• Identify and troubleshoot instrumentation assay or workflow issues; implement mitigation strategies to avoid downtime or data loss.

• Responsible for Data Management and database backups adhering to GCLP Compliance and Regulatory needs

• Work with and guide Global Instrument Leads on maintenance harmonization and documentation practices.

• Train and mentor junior staff in flow cytometry methods instrumentation and assay execution.

• Execute clinical sample testing under GCLP guidelines including PBMC and whole blood processing staining and high-parameter immunophenotyping.

• Adhere to established experimental workflows and documentation procedures while working to improve processes and documents for accuracy and efficiency.

• Design develop and optimize multiparameter flow cytometry panels and assays including ex vivo functional profiling (e.g. intracellular cytokine staining proliferation cell activation).

• Lead or support assay fit-for-purpose qualification and validation to ensure compliance with clinical standards.

• Perform data acquisition gating analysis (FCS Express) interpretation and reporting of study data.

• Contribute to analytical study documentation including SOPs study plans and study reports as needed.

• Stay current with emerging technologies reagents and industry best practices in clinical cytometry.

• Occasionally the job may require overtime work or weekend shift as needed

Heres What Youll Bring to the Table:

• Ph.D. MS or BS in Immunology Life Sciences Biology or related field; 5yr experience in translational/clinical biomarker flow cytometry

• Strong expertise with flow cytometry instrumentation (Cytek Aurora BD Symphony/Fortessa or equivalent) including set-up troubleshooting and routine maintenance.

• Proven experience in clinical laboratory environments with adherence to GCLP or other regulated standards.

• Demonstrated success in designing developing and validating multiparameter flow cytometry assays for clinical applications.

• Hands-on experience in immunology-based functional assays (intracellular cytokine staining T cell immunophenotyping receptor occupancy assays).

• High proficiency with flow cytometry analysis software (FCS Express FlowJo OMIQ) and data interpretation.

• Strong organizational computational and documentation skills (Excel GraphPad Prism PowerPoint Word).

• Excellent written presentation and interpersonal communication skills; ability to collaborate effectively across teams and with external partners.

• Track record of flexibility problem-solving and adaptability to shifting priorities in a fast-paced environment.

Pay & Benefits

At Moderna we believe that when you feel your best you can do your best work. Thats why our US benefits and global well-being resources are designed to support youat work at home and everywhere in between.

• Best-in-class healthcare coverage plus voluntary benefit programs to support your unique needs

• A holistic approach to well-being with access to fitness mindfulness and mental health support

• Family planning benefits including fertility adoption and surrogacy support

• Generous paid time off including vacation volunteer days sabbatical global recharge days and a discretionary year-end shutdown

• Savings and investment opportunities to help you plan for the future

• Location-specific perks and extras

The successful candidate may be eligible for an annual discretionary bonus other incentive compensation or equity award subject to company plan eligibility criteria and individual performance.

About Moderna

Since our founding in 2010 we have aspired to build the leading mRNA technology platform the infrastructure to reimagine how medicines are created and delivered and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission values and mindsets every day our people are the driving force behind our scientific progress and our culture. Together we are creating a culture of belonging and building an organization that cares deeply for our patients our employees the environment and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer a Fast Company Best Workplace for Innovators and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine we invite you to visit to learn more about our current opportunities.

Our Working Model

As we build our company we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation teamwork and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn contribute and make a meaningful impact.

Moderna is a smoke-free alcohol-free and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry or citizenship ethnicity disability military or protected veteran status genetic information sexual orientation marital or familial status or any other personal characteristic protected under applicable is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories consistent with legal requirements.

Accommodations

Were focused on attracting retaining developing and advancing our employees. By cultivating a workplace that values diverse experiences backgrounds and ideas we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at .

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws including the Export Administration Regulations (EAR). As such employment is contingent upon the applicants ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements only individuals who qualify as U.S. persons (citizens permanent residents asylees or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.

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