Senior Scientist, Translational Pathology
Senior Scientist, Translational Pathology
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Job Description
Job Title: Senior Scientist in Translational Pathology Oncology
Location: Gaithersburg MD US
Introduction to role:
Are you ready to make a significant impact in the fight against cancer Join our Translational Pathology team in Oncology R&D where youll contribute to an industry-leading portfolio of programs. From early clinical development of novel therapeutics to supporting approved targeted therapies your work will be pivotal in advancing cancer treatment.
Accountabilities:
In this dynamic role youll leverage cutting-edge science and technology to automate laboratory workflows and enhance data accuracy. Youll generate image analysis data from immunohistochemistry images using deep learning and foundation models integrating data from pre-clinical commercial and clinical tissues. Your analysis will provide disease linkage data to guide indication selection and target patient populations measure drug target engagement and quantify changes in the tumor microenvironment. This crucial work will inform clinical decisions on therapeutically relevant doses and schedules while deepening our understanding of cancer pathway interactions to guide rational drug combinations.
Essential Skills/Experience:
Bachelors degree in a relevant field (e.g. biology computer science engineering or other relevant subject) required and 3 years relevant experience; Masters degree preferred
Expertise in implementation of laboratory automation and digital solutions
Python proficiency is required with experience in automation and pipeline development.
Working knowledge of deep learning architectures Foundation models optimization and fine tuning.
Data visualization and data science experience (R and/or python experience strongly preferred)
Desirable Skills/Experience:
Experience in image analysis (e.g. Qupath HALO/HALO link and Visiopharm)
Experience of immunohistochemistry and/or handling immunohistochemistry data
Knowledge of GxP systems and requirements
Career exposure to the pharmaceutical industry and the drug development process.
Skilled in effective communication of complex data to a non-expert.
Enthusiasm and persistence in the application of analytic methods to complex biological problems.
Capability of successfully managing multiple simultaneous projects within an agile environment.
Working effectively within cross-disciplinary science teams including with functional leaders.
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca we are driven by a vision to eliminate cancer as a cause of death. Our team is dedicated to pioneering new frontiers in oncology research fusing cutting-edge science with the latest technology to achieve breakthroughs. With multiple indications and high-quality molecules at all stages of our innovative pipeline we are committed to delivering impactful treatments. Empowered by investment and collaboration with leading medical centers worldwide we expedite research in some of the hardest-to-treat cancers. Here courage curiosity and collaboration are at the heart of everything we do.
Ready to make a difference Apply now and be part of our journey to transform cancer treatment!
Date Posted
10-Sep-2025Closing Date
24-Sep-2025Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.
Required Experience:
Senior IC
Employment Type
Full-Time
