Scientist I

Worcester, MA - USA

Monthly Salary: Not Disclosed

Posted on: 30+ days ago

Vacancies: 1 Vacancy

Job Summary

Purpose

Describe the primary goals objectives or functions or outputs of this position.

Investigate identify develop and optimize new methods and techniques to generate reliable and reproducible data in a timely manner. Read and adapt scientific literature to accomplish assignments and demonstrate broad and versatile technical expertise within discipline.

Responsibilities

Independently design develop and optimize robust analytical methods using separations-based techniques (HPLC icIEF CE-SDS) to characterize biopharmaceutical products
Implement and innovate new experimental protocols/techniques.
Understand the goal and maintain a high proficiency in his/her projects as well as the overall program.
Interpret results and draw conclusions from own multistage experiments note significant deviations then suggest design and pursue relevant experiments.
Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.
Perform routine and complex tasks competently and independently and generate reliable and consistent results.
Troubleshoot complex analytical issues and implement innovative solutions to improve method performance and efficiency.
Impact projects mostly through lab and/or pilot plant based activities.
Responsible for compliance with all applicable Corporate and Divisional policies and procedures.
Understand and adhere to corporate standards regarding code of conduct safety appropriate handling of materials controlled drug and radioactive compounds GxP compliance and animal care where applicable.

Qualifications :

Qualifications

Bachelors degree in Biochemistry Bioengineering or Pharmaceutical Sciences with 5 years of relevant experience or Masters Degree in Biochemistry Bioengineering or Pharmaceutical Sciences or equivalent education with typically two years of experience.
Theoretical and practical knowledge to carry out the job functions.
Strong understanding of protein biochemistry and analytical method development principles.
Experience in developing and optimizing methods for charge variant analysis including both icIEF and CEX techniques with the ability to transfer these methods to a QC environment.
Proficiency in AKTA purification and fractionation to support comprehensive characterization workflows.
Proficiency in operating and troubleshooting analytical instrumentation (e.g. Agilent Waters HPLC systems Maurice PA800 systems).
Experience with the qualification and validation of analytical methods in accordance with ICH FDA and USP guidelines ensuring methods are suitable for late-phase development and regulatory submissions.
Experience using automation to standardize high-throughput workflows.
Familiarity with statistical tools for data analysis Empower and regulatory guidelines.
Experience collaborating with the process development quality control and regulatory affairs teams to align analytical strategies with project timelines and goals.
Knowledge of AAV separation techniques and awareness of future advancements in the field.
Capable of providing technical guidance and mentorship to junior scientists and laboratory staff.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

Employment Type :

Full-time

PurposeDescribe the primary goals objectives or functions or outputs of this position.Investigate identify develop and optimize new methods and techniques to generate reliable and reproducible data in a timely manner. Read and adapt scientific literature to accomplish assignments and demonstrate bro...

Purpose

Describe the primary goals objectives or functions or outputs of this position.

Responsibilities

Independently design develop and optimize robust analytical methods using separations-based techniques (HPLC icIEF CE-SDS) to characterize biopharmaceutical products
Implement and innovate new experimental protocols/techniques.
Understand the goal and maintain a high proficiency in his/her projects as well as the overall program.
Interpret results and draw conclusions from own multistage experiments note significant deviations then suggest design and pursue relevant experiments.
Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.
Perform routine and complex tasks competently and independently and generate reliable and consistent results.
Troubleshoot complex analytical issues and implement innovative solutions to improve method performance and efficiency.
Impact projects mostly through lab and/or pilot plant based activities.
Responsible for compliance with all applicable Corporate and Divisional policies and procedures.
Understand and adhere to corporate standards regarding code of conduct safety appropriate handling of materials controlled drug and radioactive compounds GxP compliance and animal care where applicable.

Qualifications :

Qualifications

Bachelors degree in Biochemistry Bioengineering or Pharmaceutical Sciences with 5 years of relevant experience or Masters Degree in Biochemistry Bioengineering or Pharmaceutical Sciences or equivalent education with typically two years of experience.
Theoretical and practical knowledge to carry out the job functions.
Strong understanding of protein biochemistry and analytical method development principles.
Experience in developing and optimizing methods for charge variant analysis including both icIEF and CEX techniques with the ability to transfer these methods to a QC environment.
Proficiency in AKTA purification and fractionation to support comprehensive characterization workflows.
Proficiency in operating and troubleshooting analytical instrumentation (e.g. Agilent Waters HPLC systems Maurice PA800 systems).
Experience with the qualification and validation of analytical methods in accordance with ICH FDA and USP guidelines ensuring methods are suitable for late-phase development and regulatory submissions.
Experience using automation to standardize high-throughput workflows.
Familiarity with statistical tools for data analysis Empower and regulatory guidelines.
Experience collaborating with the process development quality control and regulatory affairs teams to align analytical strategies with project timelines and goals.
Knowledge of AAV separation techniques and awareness of future advancements in the field.
Capable of providing technical guidance and mentorship to junior scientists and laboratory staff.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

Employment Type :

Full-time

Key Skills

Laboratory Experience
Immunoassays
Machine Learning
Biochemistry
Assays
Research Experience
Spectroscopy
Research & Development
cGMP
Cell Culture
Molecular Biology
Data Analysis Skills

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About Company

AbbVie

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuro ... View more

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