Director, Enterprise Data Architecture & AI Solutions

Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: a Bristol Myers Squibb company is a dynamic biotechnology company headquartered in San Diego CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team RayzeBio aims to be the global leader in radiopharmaceuticals.

RayzeBio is seeking a Director Enterprise Data Architecture & AI Solutions to architect integrate and scale data and AI capabilities supporting our mission to advance next-generation radiopharmaceuticals. This highly visible leadership role spans cross-functional teamsincluding Commercial Medical Affairs Clinical Operations Early Development and Manufacturingwith a sharp focus on harmonizing enterprise data architecture and accelerating the application of AI/ML for real-world impact.

The ideal candidate combines technical acumen with systems integration expertise and stakeholder savvy enabling both near-term wins and strategic transformation across RayzeBios rapidly growing organization.

The candidate will collaborate with BMS and the BI&T team to ensure all initiatives are not duplicative and are leveraging BMS know how and capabilities as appropriate.

The selected candidate will be required to travel regularly to all three sites (San Diego Indianapolis and Princeton) collaborating with teams across RayzeBio and BMS spending 30% of the time at one of these three sites.

Key Responsibilities

Enterprise Data Architecture & Platform Enablement

• Design build and continuously improve RayzeBios data lakehouse architecture to unlock analytics reporting and AI for enterprise users.

• Develop enterprise data models and semantic layers tailored for radiopharmaceutical workflows enabling scalable self-service analytics and operational insights.

• Define integration strategy across enterprise applications (clinical ERP CRM manufacturing compliance) balancing traceability integrity and regulatory requirements.

Applied AI/ML Solution Design

• Identify and evaluate high-value opportunities for AI/ML in early development clinical operations supply chain commercial analytics and scientific knowledge management.

• Lead solution design for practical AI/ML pilotscoordinating in-house or external partners ensuring alignment with RayzeBios digital and enterprise standards.

• Establish data readiness protocols for machine learning (annotation pipeline integration model monitoring/feedback and secure deployment).

Enterprise Systems Integration & Scale-Up

• Own enterprise systems integration dataflow design and harmonization as RayzeBio transitions from pre-commercial to commercial-stage operations.

• Implement master data management solutions supporting unified product customer clinical trial and manufacturing data domains.

• Collaborate with platform engineering infrastructure and partner teams to maximize interoperability and leverage best-in-class/reusable assets.

Governance Quality & Compliance

• Lead metadata management master data governance and stewardship processesensuring alignment with GxP privacy and commercial compliance requirements.

• Set and monitor high standards for data quality system validation and audit-readiness in collaboration with business and technical stakeholders.

• Champion cross-functional data governance (ownership access lineage) in a highly regulated complex data ecosystem.

Stakeholder Leadership & Team Growth

• Serve as strategic advisor on data analytics and AI readinesssupporting business R&D and executive teams with actionable architectural guidance.

• Influence and align cross-functional partners toward shared goals and enterprise data priorities; champion digital-first and Gen AI-enabled innovations.

• Establish and maintain strong relationships with BMS stakeholders

• Recruit onboard and mentor a small high-impact team as RayzeBio scales.

Required Qualifications

• BS Degree

• Minimum 10 years in data architecture analytics platform design or commercial data operationsideally within biotech pharma or healthcare.

• Proven record designing and scaling cloud-native data platforms/data models in multifaceted settings (including early-stage or growth-phase companies).

• Experience driving requirements definition collaborating with engineering and integrating complex heterogeneous data systems.

• Deep understanding of oncology or radiopharmaceutical data (commercial clinical medical or R&D).

• Demonstrated ability to operate independently and prioritize in a lean entrepreneurial environment.

• Strategic and systems-oriented with a passion for building scalable solutions and driving cross-enterprise alignment.

• Energetic self-starter-comfortable managing uncertainty setting priorities and influencing senior stakeholders.

• Highly collaborative; able to synthesize diverse viewpoints and translate ambiguous needs into concrete data/AI roadmaps.

• Pragmatic communicatoradept at concise documentation presenting actionable concepts and driving stakeholder engagement.

Preferred Experience

• Experience in oncology-driven biotech or pharma especially pre-commercial/early commercial stage.

• Working familiarity with life sciences regulatory frameworks (GxP privacy retention commercial).

• Direct exposure to ML/AI in healthcare (predictive analytics NLP Gen AI or decision support).

• Hands-on prototyping experience (Databricks cloud notebooks automation tools etc.).

• Led or contributed to AI/ML/data platform initiatives within cross-functional/product teams.

Why Join RayzeBio

This is a rare opportunity to lead the AI transformation of a high-growth biotech directly impacting our programs and patients and shaping the future of data-driven medicinesupported by the vision and resources of Bristol Myers Squibb. Selective hybrid flexibility may be considered as noted above.

RayzeBio and Bristol Myers Squibb are equal opportunity employers. All employment decisions are made without regard to race color religion gender sexual orientation gender identity age national origin or disability status.

#RayzeBio

If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job such as required skills where the job is performed the employees work schedule job-related knowledge and experience. Final individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical pharmacy dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability life insurance supplemental health insurance business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays Global Shutdown Days between Christmas and New Years holiday up to 120 hours of paid vacation up to two (2) paid days to volunteer sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement fertility/infertility benefits support for traveling mothers and child elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture promoting global participation in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential site-by-design field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles onsite presence is considered an essential job function and is critical to collaboration innovation productivity and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position please visit this page for important additional information: data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.