Senior Principal Scientist, Preclinical Safety & Translational Sciences-Translational Pharmacokinetics/Pharmacodynamics
Senior Principal Scientist, Preclinical Safety & Translational Sciences-Translational Pharmacokinetics/Pharmacodynamics
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$ 137000 - 235750
1 Vacancy
Job Description
At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at
Job Function:
Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function:
Pharmacokinetics & PharmacometricsJob Category:
Scientific/TechnologyAll Job Posting Locations:
San Diego California United States of America Spring House Pennsylvania United States of AmericaJob Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.
Purpose: The Senior Principal Scientist will be a key member of discovery project teams and interact closely with biology chemistry and other drug metabolism and pharmacokinetic (DMPK) project members to help craft the most appropriate preclinical and early clinical studies and the associated quantitative model-based analyses to advise candidate selection and dosing recommendations. Modeling approaches used may include physiologically-based pharmacokinetic modeling mechanistic PK/PD modeling and/or systems pharmacology modeling to help (a) predict preclinical and clinical PK profiles (b) quantify exposure/ response relationships for target engagement biomarkers efficacy and potential adverse effects and (c) guide in vivo and in vitro experimental designs that will be most informative for modeling.
We are searching for the best talent for a Senior Principal Scientist Preclinical Safety & Translational Sciences-Translational Pharmacokinetics/Pharmacodynamics to be located in Spring House PA or La Jolla CA.
You will be responsible for:
- Applying Pharmacokinetic/Pharmacodynamic (PK/PD) modeling to drive project team decisions from early discovery through early clinical studies.
- Contributing to guide modeling and simulation strategies within the organization.
Qualifications / Requirements:
Education:
- PhD in Pharmacology Engineering Mathematics Physics or a related field with 6 years of relevant industry experience OR a Masters degree with 8 years of relevant industry experience is required.
Experience and Skills:
- Strong familiarity with principles of pharmacokinetics and pharmacodynamics and experience performing PK and/or PK/PD modeling is preferred.
- Proven skills in mathematical modeling and simulation supported by peer-reviewed publications is highly desired.
- Excellent interpersonal organizational oral/written communication and teamwork skills are required.
Other:
- This position may require up to 10% travel.
The anticipated base pay range for this position is $137000 to $235750.
The Company maintains highly competitive performance-based compensation programs. Under current guidelines this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporations performance over a calendar/performance year. Bonuses are awarded at the Companys discretion on an individual basis.
- Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical dental vision life insurance short- and long-term disability business accident insurance and group legal insurance.
- Employees may be eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)).
- Employees are eligible for the following time off benefits:
- Vacation up to 120 hours per calendar year
- Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington up to 56 hours per calendar year
- Holiday pay including Floating Holidays up to 13 days per calendar year of Work Personal and Family Time - up to 40 hours per calendar year
- Additional information can be found through the link below. compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.
This job posting is anticipated to close on 06/30/2025. The Company may however extend this time-period in which case the posting will remain available on to accept additional applications.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.
#LI-Hybrid
Required Experience:
Staff IC
Employment Type
Full-Time
