Research Assistant - MEDIC (Research Institute)
Research Assistant - MEDIC (Research Institute)
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Job Description
Job Description
RESEARCH INSTITUTE OF THE MUHC
The Research Institute of the McGill University Health Centre (RI-MUHC) is a world-renowned biomedical and hospital research centre. Located in Montreal Quebec the Institute is the research arm of the McGill University Health Centre (MUHC) affiliated with the Faculty of Medicine at McGill University. The RI-MUHC is supported in part by the Fonds de recherche du Qubec - Sant (FRQS).
Position summary
We are working on a new mRNA-based gene therapy for a severe genetic disease. The mRNAs encoding a wildtype gene which is mutated in the patients will be delivered to the cells by transfection or to a mouse via injection. Subcellular localization in cells and the effect of the wildtype protein on the phenotype of the patient-derived cells will be mice we will first study the distribution and stability of the delivered mRNA in various tissues. Then we will use the mouse model of the disease and will study if and how wildtype mRNA rescues mutant mouse phenotype.
We are looking for an MSc part-time research assistant with a strong expertise in immunofluorescence including confocal imaging.
General Duties
Tissue culture of various cell lines and cell transfections
Immunofluorescence microscopy of the transfected and endogenous proteins
Tissue processing and immunodetection
Analysis of the results including graphing and statistical analysis
Accurate and timely reports including continuous lab book updates
Participation in the lab meetings
Student teaching and supervision.
Required Skills
Excellent communication and interpersonal skills
Excellent skills in English and/or French both spoken and written
Ability to work independently or with teams with minimum supervision
Ability to analyze and summarize scientific data in a presentable format.
Employment Type
Unclear
