Molecular and Cell Biology Senior Research Scientist
Molecular and Cell Biology Senior Research Scientist
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Job Description
Job Description
General Summary:
Our Human Disease Modelling group is seeking an innovative and dynamic Senior Research Scientist to play a pivotal role in expanding our capabilities in disease-relevant human cell models at the Oxford Research site. Successful candidates would help us utilise a range of technologies to build such models that can be leveraged to test therapeutic hypotheses discover novel target biology characterise potential drug candidates and develop translational biomarkers. This position will involve working in close collaboration with other researchers and across drug discovery disciplines to ensure that we deliver medicines that treat the underlying cause of serious diseases and provide transformative benefits for our patients.
Key responsibilities
- Independently design and (where appropriate) execute and elaborate technically challenging experiments using disease-relevant cell-based models to test therapeutic hypotheses
- Champion and leverage cutting-edge molecular cell biology techniques and technologies for in vitro disease modelling
- Effectively distil complex multi-dimensional data and results into concise concepts and propose strategic and experimental actions
- Proactively communicate and work highly effectively within and between teams
- Collaborate extensively and work on shared projects with other scientific colleagues and cross-functional teams including others in the Biology Dept and beyond
Key requirements
- PhD in a relevant Biological Science (e.g. Molecular or Cellular Biology) or equivalent years of experience in an industry setting
- Strong cell biology background with experience culturing hiPSCs and/or a broad range of cell systems such as human primary cell systems or organoids
- Experience in multi-parametric flow cytometry and other assay formats such as high-throughput imaging single-cell technologies to characterise disease mechanisms at the cellular level
- Versatile molecular biology experience including qPCR cloning Western Blot aLISA IHC and other cellular assays
- Proven track record for solving complex scientific problems and delivering high-quality results as demonstrated through an excellent publication history supported by evidence of major individual contributions
- Very strong verbal and written communication and teamwork skills
- Motivated and curious; excellent team player happy to work across a broad range of biological subjects and projects to identify the molecular drivers of disease.
#LI-onsite; LI-SG-1
Flex Designation:
On-Site DesignatedFlex Eligibility Status:
In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Required Experience:
Senior IC
Employment Type
Full-Time
