Research Fellow, Microbiology/Molecular Biology [LKCMedicine]
Research Fellow, Microbiology/Molecular Biology [LKCMedicine]
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
Lee Kong Chian School of Medicine is recruiting a Research Fellow for the Respiratory and Infectious Diseases Programme Laboratory of Antimicrobial Resistance and Drug Discovery under Professor Pablo Bifani.
The lab is working in applied phage biology with the aim of developing recombinant phages for therapeutic and/or diagnostic purposes. These phages are to be used to treat patients affected by otherwise untreatable multidrug resistant organisms or recalcitrant bacterial infections. The successful development of phages with therapeutic potentials could have a direct impact on life-saving or quality of life improvement. The job entails working with Gram positive and Gram negative bacteriophages.
Key Responsibilities:
Carry-out standard microbiology techniques bacterial cultures and phage production isolation characterization etc. The focus of the job will be on the genetic manipulations/engineering of selected bacteriophages. These will include knock-out knock-in mutagenesis etc.
Responsible for the phage recombinant work in the lab
Bacterial cultures
Phage Target deconvolution (understanding mechanisms of action and resistance of selected phages)
Design and conduct experiments including data collection and analysis
Knowledge of bioinformatic tools would be helpful
Summarize and present the data in lab meetings
Develop new research techniques and approaches
Perform maintenance of inventory and procurement of laboratory consumables
Manage the grant and basic logistical requirements associated with the project
Ensure safe technical practices and procedures
Key Competencies and Requirements:
PhD degree in Biomedical Sciences or related fields
Expected to have a background working with bacteria and have a strong background and interest in molecular including recombinant work genomic and transcriptomic.
Knowledge or expertise working with bacteriophages will be an advantage
Willing to learn and feel comfortable working with various bacteria (drug resistant K. pneumoniae Acinetobacter or mycobacterium abscessus others)
Highly adaptable at working with different organisms and techniques
Collaborative spirit with internal and external collaborators
Employment Type
Full-Time
