Associate Researcher (Dr Mayberg's Lab) - Neurology

The Center for Advanced Circuit Therapeutics (C-ACT) at The Icahn School of Medicine at Mount Sinai is seeking an Associate Researcherto perform toolbox development for multimodal imaging processing including structural diffusion and functional brain images. Specific technical skills are required including Python programming for automated imaging data preprocessing image visualization and implementing statistical analysis. Projects involve the development and implementation of treatment selection biomarkers individualized multimodal surgical targeting methods longitudinal outcome metrics across a wide range of neuropsychiatric disorders including Depression OCD Movement disorders and Epilepsy. This is an excellent opportunity to participate in cutting-edge imaging research as a member of a multidisciplinary research team of technical and clinical experts with access to state-of-the-art imaging equipment.

This individual will be jointly supervised by Dr. Ki Sueng Choi imaging leader at C-ACT and Dr. Helen Mayberg Director of C-ACT and will have the opportunity to interact with a diverse team of investigators with complementary expertise in neuroimaging psychiatry neurology neurosurgery neuroengineering computational neuroscience and bioinformatics.

The Center for Advanced Circuit Therapeutics (C-ACT) is a centralized research unit embedded within the Clinical Center for Neuromodulation and it is based at Mount Sinai West. The Center supports research and clinics using imaging invasive and noninvasive electrophysiology performance and behavioral metrics computational modeling and clinical and research bioinformatics involving surgical and nonsurgical neuromodulation patients. This core facility will enable development and testing of new brain-tuning strategies to accelerate the delivery of state-of-the art individualized care for patients with advanced neuropsychiatric disordersbe it those where brain stimulation therapies are already clinically available such as Parkinsons disease and epilepsy or more experimental applications such as depression OCD eating disorders and addiction. Developing and testing next-generation implantable devices computation-based algorithms for treatment delivery and clinical piloting of novel applications will complement ongoing evidence-based care for established uses of DBS and other neuromodulation strategies such as MR-guided focus ultrasound and TMS.

• Programming to develop an automated image preprocessing pipeline
• Programming to implement the existing surgical targeting algorithm
• Programming to implement treatment selection imaging biomarkers
• Multimodal imaging (MRI CT and PET) data preprocessing
• Real-time imaging data processing in the operating room and validate the results for DBS surgical targeting applications
• Performs other related duties.

• Bachelors degree in Computer Science Engineering Neuroscience or a related field focusing on medical image analysis and programming related to neuroimaging or related field preferred or combination of relevant research experience and education
• Candidates with experience coding in Python Matlab and/or shell script and image processing software packages (Afni MRTrix FLS SPM Freesurfer etc.)
• 0-2 years of research/laboratory experience