Senior Principal Scientist, Biological Network Analytics
Senior Principal Scientist, Biological Network Analytics
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$ 137000 - 235750
1 Vacancy
Job Description
At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at
Job Function:
Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function:
Biological ResearchJob Category:
Scientific/TechnologyAll Job Posting Locations:
Cambridge Massachusetts United States of America Spring House Pennsylvania United States of AmericaJob Description:
About Innovative Medicine:
Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.
Purpose:
We are seeking an innovative collaborative computational biologist to be part of the Biological Network Analytics team within the broader Multiomics Discovery team which is responsible for addressing omics and imaging related questions throughout the drug discovery process (from novel target identification and reverse translation to compound optimization) using various high-throughput and high-dimensional technologies. The successful candidate has a strong background in quantitative omics analysis within a drug discovery context. They will need to partner effectively with wet-lab teams to design appropriate experiments analyze data interpret results and communicate findings. As the domain is inherently interdisciplinary they will need to interact with project leads other data scientists IT statisticians and thus excellent cross-functional communication is an integral part of the desired skill set.
This role will directly support the broader Multiomics Discovery efforts through integration and analysis of multiple high dimensional biology datasets within the Biological Network Analytics group and contribute to the understanding of complex biology through advanced data analysis methods.
You will be responsible for:
- Design develop and validate sophisticated models and algorithms to characterize biological processes and networks at the system level
- Architect strategies for integrating large-scale datasets including NGS proteomics high-content imaging and other modalities across multiomics platforms
- Apply network analysis and systems biology principles to identify key pathways and interactions critical to disease pathogenesis
- Collaborate with wet lab teams for experimental design and with data scientists IT statisticians and external partners to translate insights into actionable hypotheses
- Support therapeutic project teams with data-driven recommendations fostering innovation in target discovery biomarker development and compound optimization
- Communicate findings through presentations executive summaries and publications
- Lead internal and external innovation partnerships
Qualifications / Requirements:
Education:
- A minimum of a Bachelors degree is required
- Advanced degree (PhD) in Cell Biology Molecular Biology Computational Biology Bioinformatics or related discipline is highly preferred
Required:
- Minimum 8-10 years of experience in biotech or pharmaceutical industry
- Proven expertise in systems biology network modeling and multiomics data integration
- Strong programming proficiency in Python R and relevant analysis tools
- Knowledge of machine learning algorithms statistical modeling and unsupervised analysis techniques
- Demonstrated leadership in developing innovative algorithms models and analytical frameworks
- Exceptional communication skills with a track record of publishing impactful research and effectively guiding cross-disciplinary teams
- Experience managing complex projects and multi-stakeholder collaborations
- Experience as a problem solver and team collaborator; able to facilitate understanding between biologists and data scientists
- Up to 10% travel Domestic & International
Preferred:
- Understanding of disease biology preferably in immunology oncology or neuroscience
- Expertise in single cell and spatial omics technologies
- Knowledge of cellular assay development and applications in drug discovery
- Track record of integrating external collaborations into research programs
- Strong background in statistical analysis and data visualization
- Experience with cloud computing HPC infrastructure and workflow management tools (e.g. Nextflow)
The anticipated base pay range for this position in the US is $137000 to $235750
The Company maintains highly competitive performance-based compensation programs. Under current guidelines this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporations performance over a calendar/ performance year. Bonuses are awarded at the Companys discretion on an individual basis.
Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical dental vision life insurance short- and long-term disability business accident insurance and group legal insurance.
Employees may be eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)).
Employees are eligible for the following time off benefits:
- Vacation - up to 120 hours per calendar year
- Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
- Holiday pay including Floating Holidays - up to 13 days per calendar year
- Work Personal and Family Time - up to 40 hours per calendar year
For additional general information on company benefits please go to: job posting is anticipated to close on August 12 2025. The Company may however extend this time-period in which case the posting will remain available on to accept additional applications.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.
#LI-Hybrid
The anticipated base pay range for this position is :
$00Additional Description for Pay Transparency:
Subject to the terms of their respective plans employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical dental vision life insurance short- and long-term disability business accident insurance and group legal insurance. Subject to the terms of their respective plans employees are eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Companys long-term incentive program. Subject to the terms of their respective policies and date of hire Employees are eligible for the following time off benefits: Vacation 120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington 56 hours per calendar year Holiday pay including Floating Holidays 13 days per calendar year Work Personal and Family Time - up to 40 hours per calendar year Parental Leave 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave 10 days Volunteer Leave 4 days Military Spouse Time-Off 80 hours Additional information can be found through the link below. Experience:Staff IC
Employment Type
Full-Time
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