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Job Profile:

Job Summary:

The Carbone Cancer Center has an opportunity for a Client-Based Researcher I position who will work with the faculty leader Dr. Josh Lang in the fields of Human Molecular Biology and Cellular Immunology at the UW Carbone Cancer Center (UWCCC) as a member of the Circulating Biomarker Core (CBC). The focus of the CBC is to provide sample processing and analysis services to members of the UWCCC as well as the wider non-UW research community in-line with the development and clinical translation of biomarkers from the circulation that can predict or detect therapeutic resistance in patients with solid tumor diseases. Circulating biomarkers are evaluated on clinical specimens primarily patient blood draws through a series of sample processing steps including ficoll density centrifugation magnetic depletion of normal blood cells using standard MACS columns magnetic enrichment and protein staining or nucleic acid (DNA/mRNA) extraction of metastatic tumor cells using either a customized pipetting robot or a handheld microfluidic device. Analytical systems include fluorescence microscopy image acquisition raw image conversion into quantitative data using both automated image processing algorithms and manual review of identified objects.
Characterization of mRNA is achieved with reverse-transcription quantitative PCR (RT-qPCR). With the ultimate goal of implementing these circulating biomarker diagnostics into clinical practice the CBC is also actively developing the controls and analytical validation datasets required for regulatory approval.
Our team of highly cooperative researchers coordinate the receipt processing and analysis of 10-20 patient samples each week testing a number of different protein and nucleic acid biomarkers for numerous different projects involving basic research and clinical trials.

This position requires work to be completed onsite at a designated campus work location.

Key Job Responsibilities:

• Identifies concerns and recommends solutions to leadership

• Prepares reports and materials and disseminates information to appropriate entities

• Assists with the development of research methodologies and procedures according to client-based objectives and specifications

• Trains individuals and groups on equipment operations research protocols and techniques within a specialized laboratory or research area

• Collects and analyzes basic research data conducts experiments and interviews and documents results according to established policies and procedures

• Reviews and edits research protocols under general supervision

Department:

School of Medicine and Public Health Carbone Cancer Center CORE Circulating Biomarker Core: Our mission is a commitment to defeating cancer through rapid application of groundbreaking research prevention and treatment. The University of Wisconsin (UW) Carbone Cancer Center has been an NCI-Designated Comprehensive Cancer Center since 1973. UW Carbone is an integral part of the UW School of Medicine and Public Health and UW Health bringing together more than 330 physicians and scientists from 50 departments and nine schools to conduct research and translate laboratory discoveries into new patient treatments. UWCCC builds community by creating a collaborative respectful and welcoming environment in which all faculty students and staff will thrive.

Compensation:

The starting salary for the position is $45000; but is negotiable based on experience and qualifications.

Preferred Qualifications:

- Previous experience in molecular biology methods next generation sequencing and immunology.
- Experience with microfluidic technologies and fluorescence microscopy as well as a circulating tumor cell research background.
- Previous experience in flow cytometry.

Education:

Bachelors Degree Preferred with a focus in Molecular Biology Biochemistry or other closely related biological science preferred.

How to Apply:

To apply for this position please click on the I am a current employee button or I am not a current employee button under Apply Now. You will be prompted to upload the following documents:

Cover Letter

Resume

Applicants are to submit a cover letter and resume detailing their training and experience relating to preferred qualifications referenced above. The application reviewers will be relying on written application materials to determine which qualified applicants will advance in the recruitment process. We will notify selected applicants to participate further in the selection process directly. References will be requested of final candidates. All applicants will be notified after the search is complete and a candidate has been selected.

University sponsorship is not available for this position including transfers of sponsorship and TN visas. The selected applicant will be responsible for ensuring their continuous eligibility to work in the United States (i.e. a citizen or national of the United States a lawful permanent resident a foreign national authorized to work in the United States without the need of an employer sponsorship) on or before the effective date of appointment. This position is an ongoing position that will require continuous work eligibility. If you are selected for this position you must provide proof of work authorization and eligibility to work.

Contact Information:

Devonne Tucker

Relay Access (WTRS): 7-1-1. See RELAYSERVICE for further information

Institutional Statement on Diversity:

Diversity is a source of strength creativity and innovation for UW-Madison. We value the contributions of each person and respect the profound ways their identity culture background experience status abilities and opinion enrich the university community. We commit ourselves to the pursuit of excellence in teaching research outreach and diversity as inextricably linked goals.

The University of Wisconsin-Madison fulfills its public mission by creating a welcoming and inclusive community for people from every background - people who as students faculty and staff serve Wisconsin and the world.

The University of Wisconsin-Madison is an Equal OpportunityEmployer.

Qualified applicants will receive consideration for employment without regard to including but not limited to race color religion sex sexual orientation national origin age pregnancy disability or status as a protected veteran and other bases as defined by federal regulations and UW System policies. We promote excellence by acknowledging skills and expertise from all backgroundsand encourage all qualified individuals to apply. For more information regarding applicant and employee rights and to view federal and state required postings visit the Human Resources Workplace Poster website.

To request a disability or pregnancy-related accommodationfor any step in the hiring process (e.g. application interview pre-employment testing etc.) please contact the Divisional Disability Representative (DDR)in the division you are applying make your request as soon as possible to help the university respond most effectively to you.

Employment may require a criminal background check. It may also require your references to answer questions regarding misconduct including sexual violence and sexual harassment.

The University of Wisconsin System will not reveal the identities of applicants who request confidentiality in writing except that the identity of the successful candidate will be released. See Wis. Stat. sec. 19.36(7).

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