Senior Scientist I, Protein Mass Spectrometry
Senior Scientist I, Protein Mass Spectrometry
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
$ 85400 - 158600
1 Vacancy
Job Description
Band
Level 3Job Description Summary
This position will be located at the San Diego site and will not have the ability to be located remotely. Please note that this role would not provide relocation and only local candidates will be considered.Internal Title: Senior Scientist I
If you are curious scientifically minded and want to positively impact society by speeding delivery of novel therapies to patients then look no further. Novartis is the place to be. As a Senior Scientist I at the Novartis Biologics Research Center in San Diego you will have the opportunity to make a difference. If you have a collaborative nature a commitment to teamwork across an organization and a relentless focus on improving patient care we want you to apply.
The Analytics Bioanalytics and Formulations group at Novartis San Diego is seeking a highly skilled motivated and detailed oriented scientist to support biotherapeutics drug discovery and gene therapies this laboratory-based Senior Scientist I role you will apply your hands-on expertise to the bioanalysis of large molecule therapeutics including gene therapies cell therapies antibody-drug conjugates bi-trispecific/ScFV antibodies oligonucleotides/siRNA and proteins. You will work with teams of research and discovery scientists to develop and implement stage-appropriate large molecule assays for characterization and to support pharmacokinetic pharmacodynamic and immunogenicity studies for numerous projects as they progress through the research and development pipeline. Additionally you will contribute to new technology platform evaluations to improve support for challenging new therapeutic modalities.
Job Description
Key Responsibilities:
- Independently conceives develops and executes protein characterization and proteomics-based experiments (particularly targeted workflows in biological matrices)
- Analyzes and interprets data provides conclusions and informs next level experiments
- Configures operates and troubleshoots LC/MS and LC/MS/MS instrumentation
- Performs a broad range of protein-based sample processing techniques and independently implements new techniques
- Maintains an accurate and detailed notebook documents experiments and conclusions
- Effectively communicates results and conclusions through reports and presentations
Essential Requirements:
- A Bachelor or Masters degree in biology sciences chemistry analytical chemistry or related discipline
- At least 2 years of academic or industry laboratory experience
- Ability to design and conduct experiments under minimal supervision and to analyze interpret and communicate data to colleagues
- Proficiency in standard sample processing techniques for proteomics and general protein analysis (ex. Protein extraction from biological matrices enzymatic digestion SPE chemical labeling immunoprecipitation enrichment and fractionation)
- Competence in characterizing proteins by LC/MS and LC/MS/MS is required
- Experience in the set up and operation of HPLCs (particularly nanoLC) and mass spectrometers for protein and peptide analysis
- Troubleshoot experiments and instrument issues
- Applied knowledge of MS control and data analysis software examples include: Xcalibur Analyst Proteome Discoverer Skyline BioPharma Finder Sequest
- Excellent technical ability attention to detail and an eagerness to learn new thing
- Agility and willingness to learn implement and teach new bioanalytical techniques to support the evolving portfolio is essential
Desirable Requirements:
- Prior experience in development of targeted analysis of proteins (MRM and PRM) in cells biological fluids and tissues is highly desired
- Proficiency in cell culture and biochemical techniques are highly desired
The salary for this position is expected to range between $85400 and $158600 per year.
The final salary offered is determined based on factors like but not limited to relevant skills and experience and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and depending on the level of the role eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health life and disability benefits a 401(k) with company contribution and match and a variety of other addition employees are eligible for a generous time off package including vacation personal days holidays and other leaves.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment hiring training promotion or other employment practices for reasons of race color religion gender national origin age sexual orientation gender identity or expression marital or veteran status disability or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If because of a medical condition or disability you need a reasonable accommodation for any part of the application process or in order to perform the essential functions of a position please send an e-mail to call 1 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Range
Skills Desired
Analytical Skill Analytical Skill Analytical Thinking Chemical Biology Chemistry Clinical Research Clinical Trials Collaboration Communication Skills Curiosity Data Data Analysis Design Of Experiments Detail-Oriented Diversity & Inclusion Drug Discovery Ethics Gene Therapy Immunology Laboratory Lifesciences Machine Learning (Ml) Mammalian Cell Culture Medical Research Molecular Biology 11 moreRequired Experience:
Senior IC
Employment Type
Full-Time
