Senior Scientist I, Analytical Research and Development (Synthetic Molecules)
Senior Scientist I, Analytical Research and Development (Synthetic Molecules)
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1 Vacancy
Job Description
For the Senior Scientist I position we are seeking a highly motivated candidate who can conceive implement and execute novel scientific research and development. Independently develop and optimize new methods and techniques to generate reliable and reproducible data in a timely manner demonstrate broad versatile technical expertise. They should possess understanding of core discipline and support early phase development of New Chemical Entities (NCEs) drug substance in both preclinical and clinical and collaborate within the global Analytical R&D organization and with R&D cross-functional partners such as Pre-Clinical Safety (PCS) Process Chemistry Process Engineering Drug Product Design Development (DPDD) Quality Assurance (QA) and CMC-Regulatory.
This position will focus primarily on transitioning NCEs from Discovery into Development Sciences and the individual will independently serve as an Analytical Research and Development representative in a highly cross-functional team which includes Discovery Process Chemistry Quantitative and Translational ADME Sciences (QTAS) Safety Pharmacology Pre-Clinical Safety (PCS) and Molecular Profiling and Drug Delivery (MPDD). Candidates should be comfortable discussing organic chemistry topics relevant to analytical chemistry such as stereoisomers common functional groups and pKa values. Experience with chromatographic analysis (such as HPLC or GC) and Mass Spectrometry is preferred but not required.
Responsibilities
Apply analytical separation and detection modes for complex impurity profiling of pharmaceutical drug substances to further the understanding of emerging non-GMP and cGMP manufacturing processes.
Responsible for leading the analytical aspects of a project while working with other functional areas to advance projects through the development pipeline.
Utilize understanding of a range of analytical techniques to conduct research and development studies related to small-molecule drug substances intermediates starting materials impurities and impurity profiling.
Support new product development with advanced method development and validation technical transfer packages and generation of technical data in support regulatory requirements.
Highly autonomous and productive in performing laboratory research or method development requiring only minimal direction from or interaction with supervisor.
Formulate conclusions and design follow-on experiments based on multidisciplinary data.
May initiate new areas of investigation that are scientifically meaningful reliable and can be incorporated directly into a research or development program.
Process interpret and visualize data to facilitate project team decisions.
Communicate and collaborate with cross-functional groups and departments especially process chemistry process engineering and technical operations.
Routinely demonstrate scientific initiative and creativity in research or development activities and maintain a high level of productivity in the lab.
Responsible for method development testing procedures and implementation of analytical control strategies to help the advancement of drug discovery candidates.
Raises the bar and is never satisfied with the status quo.
Understand and adhere to corporate standards regarding code of conduct safety appropriate handling of materials controlled drug and radioactive compounds and GxP compliance where applicable.
Qualifications :
Bachelors Masters or Ph.D. in Chemistry (Analytical/Organic/Medicinal) or Pharmaceutical Sciences typically with minimum 10 (BS) 8 (MS) or 0 - 2 (Ph.D.) years related industry experience.
Strong technical background in chemistry excellent analytical problem-solving skills. Capable of independently developing and troubleshoot analytical methods.
Demonstrated experience with HPLC analysis and method development preferred along with expertise and fundamental understanding of spectroscopic techniques.
Comfortable discussing organic chemistry topics within analytical R&D and with partner functions. Hands-on experience with synthetic organic chemistry preferred.
Self-motivated hard-working detail-oriented individual able to work in a fast-paced team environment.
Experience in the use of computerized data handling systems.
High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.
Practical knowledge of organic structure functional groups chemistry and modern spectroscopic techniques as applied to small-molecule analytical analysis.
Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
Learns fast grasps the essence and can change course quickly where indicated.
Creates a learning environment open to suggestions and experimentation for improvement.
Embraces the ideas of others nurtures innovation and manages innovation to reality.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements understate or local law:
The compensation range described below is the range of possible base pay compensation that theCompany believes in good faith it will pay for this role at the time of this posting based on the job gradefor this position. Individual compensation paid within this range will depend on many factors includinggeographic location and we may ultimately pay more or less than the posted range. This range may bemodified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick)medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vestedand determinable. The amount and availability of any bonus commission incentive benefits or any otherform of compensation and benefits that are allocable to a particular employee remains in the Companyssole and absolute discretion unless and until paid and may be modified at the Companys sole andabsolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Full-time
Employment Type
Full-time
