Post-Doctoral Research Fellow - Cancer Genetics
Post-Doctoral Research Fellow - Cancer Genetics
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Job Description
Overview
A Post-Doctoral Research Fellowposition is available in the lab of David MacPhersonat Fred Hutch which is focused on the biology of small cell lung cancer (SCLC). We apply functional screens and analyses of genetically engineered mouse (GEM) and patient derived xenograft (PDX) models towards understanding how genetic alterations alter the biology of SCLC and alter sensitivity towards conventional and novel therapies. Projects use cutting-edge genomics and CRISPR screening approaches and we work closely with thoracic oncologist collaborators at Fred Hutch to help translate basic findings to the clinic. Some of these directions are supported by an NIH Lung Cancer SPORE award that promotes translational lung cancer research.
Responsibilities
The specific project will be developed by both the candidate and Dr. MacPherson based on areas of shared interest. Major areas of lab research include 1) understanding response and resistance to therapy using a combination of functional screens in vivo modeling and genomic analyses of sequentially captured patient samples 2) developing innovative liquid biopsy assays to link patient phenotypes to clinical responses and 3) modeling biologically distinct subsets of SCLC using mouse and PDX systems. Projects are typically multidisciplinary and can involve co-mentorship where appropriate. The position will require both independent research as well as the ability to collaborate closely with colleagues.
Other Expectations
- Work collaboratively within the MacPherson Lab and with Fred Hutch and external collaborators
- Apply for postdoctoral fellowships and/or career development awards
- Deeply engage with their scientific problem and drive project direction
Qualifications
MINIMUM QUALIFICATIONS:
- Recent PhD or MD in Biology or related fields
- Excellent oral and written communication skills
- Must be able to design and execute experiments interpret data and present results
- A record of publication in peer-reviewed journals with at least one lead author publication or preprint
The annual base salary range for this position is from $77976 to $95014 and pay offered will be based on experience and qualifications.This position may be eligible for relocation assistance.
Additional Information
Employment Type
Full-Time
