Sr Scientist I, Microbiology
Sr Scientist I, Microbiology
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Job Description
Purpose:
Conceive and implement novel experimental approaches to answer scientific questions. Investigate identify develop and optimize new methods and techniques. Contribute to project science in area of expertise. Develop productive collaborations and communications with other groups across science disciplines. We are looking for a Sr. Scientist with a molecular biology and microbiology background to join our peptide display hit generation team. This role is responsible for leading and managing multiple technology development projects related to phage display of peptides for therapeutic discovery including generation of phage-display peptide libraries screening against therapeutic targets and identifying pharmaceutically relevant hits. This role will also utilize our proprietary peptide microarray platform to aid in accelerating hit identification from phage display campaigns
Responsibilities:
- Lead development of in-house peptide phage-display workflows that leverage our proprietary peptide microarray platform to accelerate hit identification. Includes design and generation of phage-display libraries screening of peptide libraries against therapeutic targets next-generation sequencing library preparation and large-scale data analysis.
- Investigate state-of-the-art technologies for modifying peptide phage-display libraries using chemical modifications non-canonical amino acid incorporation etc.
- Utilize our proprietary data analysis tools to efficiently analyze data from next-generation sequencing of phage libraries and other large-scale datasets.
- Routinely demonstrate scientific initiative and creativity in research or development activities.
- Highly autonomous and productive in performing laboratory research or method development requiring only minimal direction from or interaction with supervisor.
- Formulate conclusions and design follow-on experiments based on multidisciplinary data.
- May initiate new areas of investigation that are scientifically meaningful reliable and can be incorporated directly into a research or development program.
- A primary author of publications presentations regulatory documents and/or primary inventor of patents.
- Demonstrates high proficiency across a wide range of relevant technologies.
- Maintain a high level of productivity in the lab and/or pilot plant.
- Understand and adhere to corporate standards regarding code of conduct safety appropriate handling of materials controlled drug and radioactive compounds GxP compliance and animal care where applicable.
- Direct mentorship of others
.
Qualifications :
Minimum Qualifications:
- Bachelors Degree or equivalent education and typically 10 years of experience Masters Degree or equivalent education and typically 8 years of experience PhD and no experience necessary.
- Possess thorough theoretical and practical understanding of own scientific discipline.
- Training in molecular biology and microbiology methods for the generation and screening of large-scale molecular libraries
Preferred Qualifications:
- Experience in peptide phage-display including library design and generation library screening and data analysis
- Experience with generating next-generation sequencing libraries and analysis of resulting datasets
- Skills in coding for data science (e.g. Python) and/or a willingness to learn
- Experience with automation and/or molecular barcoding for scaling molecular biology/microbiology workflows
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Full-time
Employment Type
Full-time
