Process Chemistry Senior Scientist
Process Chemistry Senior Scientist
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Job Description
Job Description
General Summary:
Vertex is seeking a talented individual to join our Manufacturing Science & Technology (MSAT) Small Molecule Drug Substance group in Boston MA as a Process Chemistry Senior Scientist. A team of highly productive results-oriented individuals the Vertex MSAT Small Molecule Drug Substance team is responsible for building and operating the global supply network that delivers our commercial active pharmaceutical ingredient (API) to patients. An exceptional chemical analytical and engineering technical aptitude as well as managerial excellence is required for successful execution of our responsibilities. Solving difficult logistical challenges technical problems and building collaborative cross-functional relationships are all key to our success.
The Senior Scientist should possess a proficient level of cGMP drug substance manufacturing understanding from a chemistry engineering and analytical perspective. The person is a key technical resource utilizing their chemistry/engineering expertise and laboratory skills to resolve production issues and continuously improve the manufacturing process and/or analytical methods. The Senior Scientist should work collaboratively with project stakeholders and has the ability to understand and communicate results to effectively address project needs.
Key Responsibilities and Technical Skills:
- Conducts/designs and interprets chemical engineering and analytical experimental procedures in the laboratory both independently or following direction from supervisor/mentor and according to established safety guidelines
- Assists in developing and executing technical transfer and process validation activities
- Provides technical support in resolving manufacturing and/or testing issues that arise
- Promotes positive and effective relationships with relevant technical individuals or teams at contract manufacturing sites
- Synthesizes or characterizes markers and reference standards when needed.
- Participates in material qualification activities and technical assessment of potential contract manufactures including performing and/or analyzing use-tests of samples in the lab
- Contributes to generation and review of technical documentation
- Will require travel periodically to contract manufacturing plants to monitor process performance or to troubleshoot manufacturing issues in the plant
- Complies with all Quality Regulatory Health Safety and Environmental responsibilities for the position
- Takes full responsibility within scope of the position to work with various stakeholders (such as Quality Supply Ops Regulatory Pharm Dev suppliers etc.) to proactively and collaboratively resolve issues that may negatively impact project timelines or deliverables
- Proactively communicates technical and operational trends orally to supervisor/team and through written reports and oral presentation
- Performs other duties as assigned
- Domestic and international travel (20% of time) is required to provide onsite support during manufacturing
Required Qualifications:
- Typically requires a Bachelors degree and 8 years of experience or a Masters degree and 5 years of experience or a PhD and 2-5 years of experience or the equivalent combination of education and experience.
- Passion for scientific knowledge
- Excellent verbal and written communication skills
- Be highly-motivated and have an excellent work ethic
Required Experience
- Experience applying statistical approaches in the design and analysis of experiments
- Experience in scale-up/late phase clinical development and technical support in manufacturing environments
- Demonstrated ability to develop solutions to complex open-ended problems with creativity and innovation
- Ability to multi-task and complete work in a reliable and consistent manner
- Appropriate computer skills to support instrumentation and data manipulation
- Must be able to demonstrate core values/leadership
- Previous experience in the biotech/pharmaceutical industry is required.
Pay Range:
$117400 - $176100Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
On-Site DesignatedFlex Eligibility Status:
In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Required Experience:
Senior IC
Employment Type
Full-Time
