Senior Scientist - Psychiatry
Senior Scientist - Psychiatry
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$ 63400 - 115000
1 Vacancy
Job Description
Scheduled Hours
40Position Summary
Alzheimers disease (AD) is a highly heterogeneous multifactorial disease. Genetic influences on AD are strong as shown by several pathogenic genes and over 50 AD loci identified through genome-wide association studies (GWAS). There are also clear sex differences in AD risk and progression. Women are at a higher risk of developing AD and present faster progression. A recent GTEx study also highlights sex differences in the genetic regulation of gene expression. Despite these established sex differences sex-specific molecular findings in AD are still limited. The objective of our team is to generate detailed sex-specific multi-tissue molecular profiles of AD and decipher the genetic architecture that underlies AD. To identify sex-specific functional mechanisms underlying the genetic architecture of AD we have generated multiple layers of -omics data including DNA methylation gene expression proteomics metabolomics and lipidomics from several large and well characterized studies. A series of well-powered sex-specific omics characterization across multiple tissues can help identify novel drug targets and provide critical insights for clinically translatable interventions for prevention and treatment. We aim to map additional GWAS loci by performing sex-specific multi-omic quantitative trait loci and co-localization for each -omic layers. We aim to identify the causal genes proteins and additional -omic analytes by performing Mendelian randomization. Analyzing such omics data will elucidate a causal path from sex-specific genetic variation to AD risk onset and progression.Collaborates on designing conducting and reporting of research projects.
Job Description
Primary Duties & Responsibilities:
- Collaborates with the PI on the design conduct and reporting of research projects.
- Assists with grant preparation and reporting. May submit grant proposals in rare circumstances with the approval of the PI Department Head and Dean.
- Prepares and submits papers on research.
- Develops hypotheses to be tested and ways of testing it.
- Complies with established safety procedures and maintaining required documentation on laboratory and specimen conditions.
- Manages research project with other institutions and investigators.
- Performs other duties as assigned.
Working Conditions:
- Works in a laboratory environment with potential exposure to biological chemical and radioactive hazards.
- Must be physically able to wear protective equipment and to provide standard care to research animals.
Required Qualifications
Education:
Phd Or Terminal Degree Or Combination Of Education And Experience May Substitute For Minimum Education.
Certifications:
Work Experience:
Skills:
Drivers License:
More About This Job
WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.Preferred Qualifications
Education:
No additional education beyond what is stated in the Required Qualifications section.
Certifications:
Work Experience:
Skills:
Analytical Problem Solving Laboratory Instrumentation Laboratory Processes Laboratory Techniques Oral Communications Teamwork Working Independently Written CommunicationGrade
R12Salary Range
$63400.00 - $115000.00 / AnnuallyThe salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including ones qualifications and performance equity with others in the department market rates for positions within the same grade and department budget.Questions
For frequently asked questions about the application process please refer to our External Applicant FAQ.
Accommodation
If you are unable to use our online application system and would like an accommodation please emailor call the dedicated accommodation inquiry number at and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and if requested reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job absent undue hardship.Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and as applicable for the position other background checks drug screen an employment and education or licensure/certification verification physical examination certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.Benefits Statement
Personal
Up to 22 days of vacation 10 recognized holidays and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan which combines employee contributions and university contributions starting at 7%.
Wellness
Wellness challenges annual health screenings mental health resources mindfulness programs and courses employee assistance program (EAP) financial resources access to dietitians and more!
Family
We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care Weve got you covered.
WashU covers the cost of tuition for you and your family including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
Required Experience:
Senior IC
Employment Type
Full-Time
