Director of Clinical Biomarkers
Director of Clinical Biomarkers
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$ 217200 - 295900
1 Vacancy
Job Description
Your work will change lives. Including your own.
The Impact Youll Make
Recursion is at the forefront of reimagining drug discovery and development through broadening the funnel of potential targets using technology and standardization to build connected data. Recursion has a strong and diverse pipeline that spans first-in-class and best-in-class assets across oncology and rare disease. As Director of Biomarkers you will serve as the Biomarker lead on clinical program teams and will be responsible for delivering on fit-for-purpose biomarker strategies that include predictive and pharmacodynamic biomarker assays. You will leverage your deep understanding of the scientific regulatory and operational aspects of biomarkers to implement appropriate measurements that enable clinical decision making and the development of safe and effective medicines to address unmet medical need.
In this role you will:
- Lead the overall biomarker strategy and execution for assigned program(s) in the Recursion portfolio by serving as the clinical biomarker lead on program/study teams.
- Develop plans collaboratively to deliver fit-for-purpose pharmacodynamic predictive prognostic and/or other biomarker assays to support decision making in early development. Work with discovery teams to support preclinical to clinical transitions of programs and align overall translational and biomarker strategies
- Partner with various research and clinical teams including Clinical Operations Stats Data Management Project Leadership etc. to contribute to biomarker-related aspects of trial design and conduct study documents (e.g. protocols study reference manuals study reports INDs etc.) trial readouts/endpoints and regulatory interactions
- Actively manage CROs vendors suppliers and other groups for assay development and qualification/validation. Oversee the operational aspects of biomarker implementation including sample logistics data management and coordination with internal teams and CROs.
- Stay current with emerging science and innovate with novel technologies and approaches to generate/analyze/apply data and derive insights on mechanisms indications combinations and patient selection/stratification.
- Present biomarker findings at key internal and external meetings
The Team Youll Join
You will join the Development Sciences team will report to the Head of Clinical Biomarkers and will be part of the Clinical Development organization at Recursion. The Development Sciences team is a group of project-facing Translational scientists that supports the transition of projects from discovery into clinical development and beyond. Core functions within this team include translational PK/PD modeling clinical pharmacology clinical bioanalysis and biomarkers. This is a collaborative group of scientists who: 1) work closely with discovery to ensure the progression of the right molecule at the right dose for the right patient 2) support IND filings and 3) ensure the continued implementation of the appropriate translational strategies for projects in clinical development. In this role you will have the opportunity to work seamlessly with the drug discovery and clinical development organizations at Recursion to ensure that we apply the best science in service of the portfolio.
The Experience Youll Need
- PhD MD or equivalent in a relevant scientific discipline with 8 years of biopharmaceutical industry experience with a solid understanding of drug discovery and early development
- Extensive experience in clinical biomarkers/diagnostics and/or translational research; Strong understanding of clinical studies and working within cross-functional study/program teams contributing to biomarker relevant documents plans operations and workstreams
- Knowledge of regulatory requirements best practices in applying translational science and biomarker assay development and validation to support global clinical trials
- Strong understanding of various technology platforms and datasets including omics for discovery validation and implementation of biomarkers; Familiarity with effectively engaging vendors and CROs providing services for biomarker assays
- Expertise in one or more of the following therapeutic areas: oncology rare disease immunology/inflammation
- Ability to think critically strategically practically to enable decision making and influence R&D teams and stakeholders; Track record in problem solving data analysis/interpretation and team science innovation
Working Location & Compensation:
This position can be based at any of our offices in Salt Lake City / New York City / Toronto / London / Oxford. Please note that we are a hybrid environment and ask that employees spend 50% of their time in the office. Relocation support can be provided for this role.
At Recursion we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role the estimated current annual base range for this role is:
$217200 - $295900 USD
$203200 - $249700 CAD
120400 - 138700 GBP
You will also be eligible for an annual bonus and equity compensation as well as a comprehensive benefits package.
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The Values We Hope You Share:
- We act boldly with integrity. We are unconstrained in our thinking take calculated risks and push boundaries but never at the expense of ethics science or trust.
- We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up speaking honestly and taking action.
- We learn actively and adapt rapidly. Progress comes from doing. We experiment test and refine embracing iteration over perfection.
- We move with urgency because patients are waiting. Speed isnt about rushing but about moving the needle every day.
- We take ownership and accountability. Through ownership and accountability we enable trust and autonomyleaders take accountability for decisive action and teams own outcomes together.
- We are One Recursion. True cross-functional collaboration is about trust clarity humility and impact. Through sharing we can be greater than the sum of our individual capabilities.
Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate support one another spend our time make decisions and celebrate collectively.
More About Recursion
Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS a platform built across diverse technologies that continuously generate one of the worlds largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale up to millions of wet lab experiments weekly and massive computational scale owning and operating one of the most powerful supercomputers in the world Recursion is uniting technology biology and chemistry to advance the future of medicine.
Recursion is headquartered in Salt Lake City where it is a founding member of BioHive the Utah life sciences industry collective. Recursion also has offices in Toronto Montral New York London Oxford area and the San Francisco Bay area. Learn more at or connect onX (formerly Twitter)andLinkedIn.
Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin age disability veteran status or any other characteristic protected under applicable federal state local or provincial human rights legislation.
Accommodations are available on request for candidates taking part in all aspects of the selection process.
Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursions internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
Required Experience:
Director
Employment Type
Full Time
