Research Fellow (Brain Delivery) - Center for Genomic Medicine - Stanton Lab
Research Fellow (Brain Delivery) - Center for Genomic Medicine - Stanton Lab
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Job Description
Mass General Brigham relies on a wide range of professionals including doctors nurses business people tech experts researchers and systems analysts to advance our mission. As a notforprofit we support patient care research teaching and community service striving to provide exceptional care. We believe that highperforming teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
For specific inquiries please email with the subject header Research Position Inquiry: Research Fellow in Delivery to the Brain. Applicants should send a cover letter CV and contact information for three professional references. Accompanying letters of recommendation are encouraged but not strictly required.The Stanton Lab in the Center for Genomics Medicine (CGM) and Department of Neurology at Harvard Medical School and Massachusetts General Hospital is seeking a highly motivated and skilled scientist to be the driver of our effort to develop new approaches for enhanced delivery to the brain towards the delivery of genetic medicines and realization of precision medicine approaches. The scientist will build on and further develop close collaborations with worldleading experts within Harvard Medical School and Massachusetts General Hospital and technology of the Stanton Lab ().
Core areas of focus will include the development of advanced preclinical screening tools generation of vectors and formulation of nanoparticles and other molecules evaluation in animal models and in vitro systems. The candidate will join a multidisciplinary and highly collaborative research environment that includes neuroscientists geneticists bioengineers computational biologists and physicianscientists at the CGM and Department of Neurology as well as at other leading academic institutions and biopharmaceutical companies.
Qualifications
Ph.D. in Chemical Engineering Bioengineering Pharmaceutical Science Neuroscience Biology or related field with deep expertise in drug transport techniques
Develop novel in vitro and in vivo assays for evaluating functionality targeting efficiency and potency of novel delivery modalities
Be interested in realizing a precision medicine approach to neurological disorders and highly practical actionable and translational research
Strong skills in rodent handling dosing (IC IV etc.) and necropsy (preferred)
Strong skills in tissue culture and bioreactor design (preferred)
Strong skills in lipid nanoparticle (LNP) formulation characterization and analysis techniques (preferred)
Strong skills in preformulation work such as solubility stability and excipient compatibility testing (preferred)
Knowledge of experimental design
Statistical and quantitative analysis skills
Basic bioinformatics skills
Selfmotivated and highly dedicated
Effective organizational and prioritization skills
Effective oral written and interpersonal communication skills
Ability to work both independently as well as collaboratively in a multidisciplinary environment
Strong skills in mathematical modeling of molecular diffusion in multiphase systems and determining primary rate limiting physical and chemical properties of model and molecules of interest (preferred)
Strong skills in integrating output of laboratory and mathematical simulations to provide drug delivery guidelines for molecular transport across multiphase systems as a function of molecular properties (preferred)
For specific inquiries please email with the subject header Research Position Inquiry: Research Fellow in Delivery to the Brain. Applicants should send a cover letter CV and contact information for three professional references. Accompanying letters of recommendation are encouraged but not strictly required.
Additional Job Details (if applicable)
Remote Type
Work Location
Scheduled Weekly Hours
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EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham our competency framework defines what effective leadership looks like by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half PeopleFocused half PerformanceFocused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance make hiring decisions identify development needs mobilize employees across our system and establish a strong talent pipeline.
Employment Type
Grant
