Executive Director Global Product Leader, Oncology R&D
Executive Director Global Product Leader, Oncology R&D
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Job Description
Job Title: Executive Director Global Product Lead Oncology R&D
Location: This role offers the flexibility to be based at: Gaithersburg MD USA & Waltham MA USA
At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue worldclass medicines in new ways combining our peoples exceptional skills with those of people from all over the globe!
We are committed to advancing the science of oncology to deliver lifechanging medicines to patients most in need. With a combinationfocused pipeline that exploits the power of six scientific platforms (ImmunoOncology Tumor Drivers and Resistance DNA Damage Response Antibodydrug Conjugates Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of cancers we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death. We currently have over 100 Phase 1 2 3 and Lifecycle Management Oncology projects in our robust pipeline. We deliver the Research & Development for Oncology through our newly created Oncology R&D Unit. This unit has responsibility for the value chain from discovery through to latestage development enabling rapid acceleration of promising earlystage assets and lifecycle management programs.
Overview:
Join us at AstraZeneca as an Executive Director Global Product Lead (GPL) in Oncology R&D. This role offers the opportunity to lead and be accountable for multiple global crossfunctional early global product teams across diverse biological mechanisms. As the CEO of the asset you will have the chance to make a big impact and be part of the team that aims to eliminate cancer as a cause of death.
The Executive Director Global Product Lead (GPL) will have overall leadership and accountability of multiple global cross functional early global product teams across diverse biological mechanisms from candidate selection through Phase III investment decision across 3 of the major platforms (IO ADC Cell Therapy). This individual will be accountable for the strategic leadership and execution for the product candidates (essentially the CEO of the asset). You will have oncology clinical drug development experience demonstrated leadership and be able to critically evaluate the science clinical data and competitive landscape that underlies these programs. You will be able to effectively communicate across a broad range of audiences and have an ability to clearly articulate project specific strategies as it relates to the overall oncology strategy.
Major Duties and Responsibilities:
Leads global product teams from preclinical candidate selection through proof of concept leading to Phase III
Investment decisions. If appropriate GPLs may have the opportunity to continue to lead assets through late development/ registration.
Single point of accountability for the strategy budget timeline and execution of a portfolio of preclinical and clinical stage therapeutic candidates.
Create integrated product development plans which are aligned with business objectives and are differentiated from competitor products.
Leads and communicates the project development strategy at governance meetings to secure funding and endorsement of the strategy.
Leads the global project team to effectively manage/mitigate/communicate risk. Responsible for monitoring emerging data and pivot when deemed necessary.
Responsible for maintaining a high degree of team effectiveness through collaboration influence and as necessary coaching and mentoring of crossfunctional team members.
Maintains relationships with external investigators to ensure projects are consistent with evolving clinical
Qualifications:
Education: Graduate degree such as a PhD PharmD or an MD/PhD is required
10 years experience leading oncology drug development
Required Experience:
Demonstrated success in developing oncology agents.
Industry experience in drug development including experience in early phase nonclinical and/or clinical drug development and regulatory knowledge.
Strong knowledge and understanding of the Oncology therapeutic area with experience in diverse biological mechanisms.
Broad understanding of the evolving clinical landscape in oncology.
Demonstrated experience leading and motivating teams in a highly matrixed environment.
Proven record of cultivating and managing internal and external crossfunctional collaborations.
Demonstrated success in influencing colleagues and senior leaders in various departments.
Must demonstrate high integrity.
Desired Skills:
Experience in the development of biologics is highly desirable.
ADC/ IO/ Radio Conjugates (T cell engagers immune redirecting agents cell therapy etc) development experience is highly desirable.
Due diligence experience as GPLs often are required to participate in business development.
Why AstraZeneca
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility.
Join us on our journey of building a new kind of organization to reset expectations of what a biopharmaceutical company can be. This means were opening new ways to work groundbreaking pioneering methods and bringing unexpected teams together. Interested Come and join our journey!
So whats next
If you are passionate about the possibilities dont hesitate in submitting an application today!
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Date Posted
09Apr2025Closing Date
31May2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:
Exec
Employment Type
Full-Time
