Principal Research Associate, Preclinical and Translational Science
Principal Research Associate, Preclinical and Translational Science
Posted on :
18-05-2025
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1 Vacancy
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Job Description
COMPANY MISSION
At eGenesis we aspire to deliver safe and effective human transplantable cells tissue and organs utilizing the latest advancements in genome editing.
POSITION SUMMARY
We are seeking an outstanding highly motivated Principal Research Associate to join our Development team. This role will support preclinical science assay optimization in the context of xenotransplantation. This position provides an excellent opportunity to help develop xenotransplantation products in an exciting and dynamic environment focused on cuttingedge molecular and cellular engineering technology.
In this role you will be part of a team responsible for generating a cell line derivation pipeline and in vitro assay optimization. The role will involve significant cell culture work in vitro and ex vivo analyses with porcine nonhuman primate and human cells and biosamples. The ideal candidate will have strong experience in cell culture and assay development preferably using flow cytometry techniques and will play a critical role in driving our xenotransplantation organ programs forward.
PRIMARY RESPONSIBILITIES
- Design execute and analyze in vitro experiments to support pretransplant screening in the context of xenotransplantation.
- Develop and optimize a cell line derivation pipeline to be used in immunological in vitro assay experiments.
- Develop and optimize assays to assess immune responses involving different kidney cell subtypes including using multicolor flow cytometry Incucyte ELISA and other techniques.
- Perform and assist with assay execution for different organ programs.
- Collaborate with crossfunctional teams (analytical development preclinical translational computational biology) to advance projects.
- Interpret experimental data and present findings to internal and external stakeholders.
- Maintain accurate and detailed laboratory records in compliance with regulatory standards.
- Contribute to the preparation of research reports and regulatory submissions.
QUALIFICATIONS
- Bachelors degree in Immunology Biology or a related field with 8 years of related experience; or masters degree with 6 years of related experience
- 46 years of handson experience in immunology within the biotech industry.
- Proficiency in immunological techniques including flow cytometry ELISAs cell culture and molecular biology methods.
- Strong understanding of the Incucyte system multicolor flow cytometry and primary cell culture.
- Sample management including collection processing storage and documentation.
- Excellent written and verbal communication skills.
- Ability to work independently and collaboratively in a fastpaced teamoriented environment.
- Demonstrated ability to manage multiple projects and meet deadlines.
Required Experience:
Staff IC
Employment Type
Full-Time
Key Skills
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