Scientist (High Throughput Screening, Antibody Discovery)
Scientist (High Throughput Screening, Antibody Discovery)
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Job Description
200 staff. Limitless Potential. One team Cancer Research Horizons.
Scientist High Throughput Screening (Antibody Discovery) Under the leadership of Nick Tribble
Salary:per annum depending on experience(dependent on experience) plus benefits (includes up to 12% pension contribution and income protection)
Reports to: Principal Scientist Antibody Discovery
Department: Research and Innovation
Contract: Permanent
Hours: Full time 35 hours per week (flexible working requests considered)
Location: Cori Building Granta Park Cambridge
Closing date: 26th May 2025 23:55. This vacancy may close earlier if a high volume of applications is received or once a suitable candidate is found therefore we strongly recommend that you apply early to avoid disappointment. If you require more time to apply as part of a reasonable adjustment please contactas soon as possible.
Visa Sponsorship: Cancer Research UK is able to consider visa sponsorship for this vacancy (conditions apply at this level). If this applies to you please ensure that this is clearly marked on your application.
Interview schedule: Initial screening interviews may be conducted via MS Teams week commencing 2nd June 2025 and in person interviews to be held at Granta Park 11th12th June 2025.
At Cancer Research UK we exist to beat cancer.
We currently have an exciting opportunity within our Drug Discovery team for an experienced Scientist to expand and enhance our capabilities in therapeutic antibody discovery.
About CRUK Drug Discovery
As the worlds biggest medical research charity weve helped bring eleven new cancer drugs to market. However there is still an urgent need to bring more effective treatments to patients faster.
We have recently developed a new approach to driving therapeutic innovation through the creation of Cancer Research Horizons (CRH). We havebrought together Cancer Research UKs established drug discovery teams under one organisation and leadership team combining our unique pipeline of cancer biology expertise and access to CRUKs worldclass academic network cutting edge technology platforms and clinical expertise to 1) bring new treatments to patients faster and 2) tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success.
Based at sites in Cambridge the CRUK Scotland Institute in Glasgow the Francis Crick Institute in London and Newcastle University Cancer Research Horizons employs 200 staff from both industrial and academic backgrounds
In this labbased role you will use your knowledge and experience with biochemical and cell based high throughput screening technology to develop and execute high throughput screening assays and associated drug discovery activities within the Antibody Discovery team (c11 people) of Cancer Research Horizons. Youll bring with you experience of developing and running cellbased assays to identify earlystage drug candidates ideally antibodies but experience of small molecules will be considered.
In return you will have the opportunity to work in an inclusive environment where we welcome creative thinking and new ideas we would welcome your input on implementation of new technologies and improvements to existing processes and infrastructure. Furthermore we actively encourage our colleagues to celebrate our science by attending conferences presenting posters giving talks at events and publishing papers.
What will I be doing
Working on the development and execution of high throughput screening assays to enable the identification and characterisation of therapeutic antibodies.
Contributing to project progression as part of a multidisciplinary team.
Utilising biochemical and cellbased assays to characterise functional properties of therapeutic antibodies (e.g. IC50 or EC50 determination).
Working with a variety of assay formats detection technologies and laboratory automation to maximise efficiency.
Maintaining relevant technical and intellectual expertise relevant to the field (e.g. assays development and antibody discovery).
Recording tracking and presenting data for project team meetings.
What skills will I need
PhD in relevant field or Degree with equivalent drug discovery experience.
Strong knowledge of biochemical and cellbased high throughput screening (HTS) technologies utilized in preclinical antibody drug discovery.
Experience of developing and running high throughput cellbased assays to identify earlystage drug candidates ideally antibodies but experience of small molecules will be considered.
Extensive experience of working with a variety of assay formats and detection technologies such as flow cytometry high content imaging ELISA MSD and HTRF assays.
Experience of applying a range of laboratory automation solutions (e.g. Viaflo Hamilton HighRes) to support drug discovery cascades is highly desirable.
Proactive with a can do attitude; with a demonstrated ability to prioritise own work effectively multitask and adapt flexibly to changing priorities.
Strength in collaborative working and proven ability to interact and effectively communicate scientific objectives and project results with colleagues.
Demonstrated interest in scientific innovation and driving new capability development to support antibody discovery
What will I Gain
Our organisation values are designed to guide all that we do.
Bold:Act with ambition courage and determination
Credible:Act with rigour and professionalism
Human: Act to have a positive impact on people
Together:Act inclusively and collaboratively
Were looking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer.
If youre interested in applying and excited about working with us but are unsure if you have the right skills and experience wed still love to hear from you.
What will I gain
We create a working environment that supports your wellbeing and provide a generous benefits package a wide range of career and personal development opportunities and highquality tools. Our policies and processes enable you to improve your worklife balance take positive steps in your career and achieve your personal wellbeing goals.
You can explore our benefits by visiting our careers web page.
How do I apply
We operate an anonymised shortlisting process in our commitment to equality diversity and inclusion. CVs are required for all applications; but we wont be able to view them until we invite you for an interview. Instead we ask you to complete the work history section of the online application form for us to be able to assess you fairly and objectively.
For more information on this career opportunity please visit our website or contact us at .
For more updates on our work and careers follow us on: Linked In Facebook Instagram X and YouTube.
Our vision is to create a charity where everyone feels like they belong benefits from and participates in the work we do. We actively encourage applications from people of all backgrounds and cultures in particular those from ethnic minority backgrounds who are currently underrepresented.
We want to see every candidate performing at their best throughout the job application process interview process and whilst at work. We therefore ask you to inform us of any concerns you have or any adjustments you might need to enable this to happen. Please contact or 0as soon as possible.
Unfortunately we are unable to recruit anyone below the age of 18 so that we can protect young people from health & safety and safeguarding risks.
Employment Type
Full-Time
