Molecular Biology / Functional Genomics Senior Research Scientist
Molecular Biology / Functional Genomics Senior Research Scientist
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$ 118500 - 177800
1 Vacancy
Job Description
Job Description
Vertex Pharmaceuticals Inc. is seeking a highly motivated and experienced Senior Scientist to join our Molecular and Cell Biology Department in San Diego. The successful candidate will play a crucial role in advancing our understanding of human genetic diseases and applying this knowledge to support innovative drug discovery and disease modeling efforts. The successful candidate will utilize advanced molecular biology technologies genomics and bioinformatics approaches to inform drug discovery strategies guide the generation of predictive disease models and evaluate therapeutic candidates.
Responsibilities:
- Design and execute complex molecular biology experiments to investigate mechanisms of genetic diseases.
- Develop and implement stateofthe art molecular biology and functional genomics approaches including CRISPR screening techniques highthroughput QPCR scRNAseq and spatial transcriptomics to understand causal disease biology and identify and validate drug targets.
- Generate analyze and interpret gene expression data using appropriate statistical and bioinformatics tools.
- Collaborate with crossfunctional teams including Computational Genomics Cell Biology and Pharmacology to advance research goals and drug development programs.
- Present research findings at internal meetings to team members collaborators and senior leadership.
Education and Experience:
- Ph.D. (or equivalent degree) in molecular biology cell biology biochemistry or related disciplines and 25 years of relevant postdoctoral employment experience or
- Masters Degree (or equivalent degree) in molecular biology cell biology biochemistry or related disciplines and 5 years of relevant employment experience or
- Bachelors Degree (or equivalent degree) in molecular biology cell biology biochemistry or related disciplines and 8 years of relevant employment experience
- Extensive knowledge and hands on experience in stateoftheart molecular biology techniques including molecular cloning PCR sequencing technologies including Illumina NGS Oxford Nanopore long read sequencing and others.
- Proficiency and hands on experience in CRISPR genome editing and functional genomics approaches.
- Experience with imagebased as well as sequencebased spatial transcriptomics technologies.
- Strong background in human genetics and disease biology.
- Experience with bioinformatic tools and data analysis.
- Excellent communication and presentation skills.
- Innovative thinking and problemsolving aptitude.
- Ability to work independently and as part of a collaborative team.
- Efficient multitasking skills
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Pay Range:
$118500 $177800Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other jobrelated factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive marketleading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a weeklong company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
OnSite DesignatedFlex Eligibility Status:
In this OnSite designated role you will work five days per week onsite with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an EVerify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Required Experience:
Senior IC
Employment Type
Full-Time
