We are Arcadia Science an evolutionary biology company founded and led by scientists. Our mission is to turn natural innovations into real-world solutions by developing systematic and quantitative approaches to leveraging biology for therapeutics R&D. We share our research as openly as possible to accelerate discovery and engage with the broader scientific community.
The Opportunity:
We are seeking an experienced Molecular Biologist to join the Core Technologies team and collaborate with scientists across the organization. Core Technologies implements scientific tools and molecular techniques to solve biological research problems with a particular focus on mapping genotype phenotype relationships.
In this role youll spearhead our efforts in mutagenesis polymorphism targeted sequencing and molecular phenotype identification. You will lead molecular assay development translating pilot projects into robust systems accessible across the company.
Our evolutionary perspective spans the tree of life and youll help drive this vision by designing experiments and developing protocols tailored to diverse non-traditional model organisms. Youll design and optimize novel molecular workflows to interrogate genotypephenotype relationships with a focus on developing NGS-based assays beyond traditional short-read sequencing. More broadly youll serve as a molecular biology expert guiding decision-making and ensuring scientific rigor across experimental efforts.
The ideal candidate is a molecular biology expert with a strong foundation in both industry and academic settings. You bring a first-principles understanding of NGS and assay development along with a clear perspective on emerging innovations across the field. As a lead experimentalist youll independently design and drive projects while providing mentorship and strategic guidance to the team.
Key Responsibilities:
Design and execute protocols for mutagenesis and targeted sequencing of polymorphisms across a broad range of unicellular and multicellular organisms.
Develop and implement quantitative and qualitative molecular assays to enable screening and functional characterization of diverse molecular phenotypes.
Ensure quality of resulting datasets is appropriate for downstream applications and assays and processes are well documented and parameterized
Independently troubleshoot challenges such as comparing orthologous techniques for capturing relevant genotypic data at higher throughput and lower cost
Prepare RNA and DNA libraries for sequencing
Automate or develop higher throughput strategies for recurring molecular biology workflows
Project manage contract work with outside consultants CROs and sequencing vendors
Manage and guide team performance and provide professional and technical mentorship
Keep detailed experimental records and documentation (SOPs) for all workflows
Ph.D. or equivalent experience in Molecular Biology or Biochemistry
At least 3 years of full-time relevant scientific experience post-PhD including leadership roles
Hands-on technical experience in the following areas: mutagenesis NGS method development and library prep optimization
Experience building and optimizing computational pipelines to analyze NGS experiments
Passionate about Tidy Data and bioinformatic workflows that follow best software development practices
Effective project management ability demonstrated by ability to scope work with key stakeholders create milestones and timelines identify blockers
Ability to align team with cross-functional goals and organize effective collaborations
An excellent verbal and written science communicator for both general and technical audiences. We expect all scientists to actively draft and openly publish their lessons
Compensation:
Successful applicants can expect to be compensated between $130000-$180000 with benefits and a highly competitive equity offering depending on experience level. The position will require the individual to be on-site at our Emeryville California headquarters.
Application Process:
Interested applicants should send a resume and a one-page cover letter that describes how the molecular biology techniques they are an expert in might advance our comparative evolutionary approach to research.
Arcadia Science is an equal opportunity workplace; we welcome people from all backgrounds and communities. We provide competitive compensation and practical benefits to keep you happy and healthy so that you can do your best work.
Please note that an offer of employment from Arcadia is contingent upon the successful clearance of a reference and background check.
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