Computational Chemistry Senior Research Scientist
Computational Chemistry Senior Research Scientist
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$ 123400 - 185100
1 Vacancy
Job Description
Job Description
We are seeking a highly motivated Computational Chemistry Senior Research Scientist to join Vertexs research site in San Diego California. This individual will be responsible for contributing to both lead identification and optimization programs using methods encompassing all computational aspects of drug discovery. This individual will work collaboratively with interdisciplinary project teams to provide expertise in cheminformatics physicsbased methods and molecular design to deliver drug candidates. Contributing to improving foundational computational capabilities across the department is preferred and achieved through collaboration with the global DCS group.
Responsibilities:
- Collaborate with scientists at our San Diego drug discovery site and across our network to maximize the impact of computational efforts on drug discovery projects
- Ensure effective interdepartmental communication and implementation of insilico work streams related to drug discovery
- Work with others in Computational Drug Design and the Chemical Data Science group to identify and apply new methodologies to increase impact of computation on drug discovery teams
- Incorporate innovative strategies and methodologies to address critical project issues
Education and Experience:
- Ph.D. (or equivalent degree) in engineering science or math and 25 years of productive relevant postdoctoral employment experience or
- Masters Degree (or equivalent degree) in similar fields and 5 years of productive relevant employment experience or
- Bachelors Degree (or equivalent degree) in similar fields and 8 years of productive relevant employment experience
- Strong experience in applying molecular modeling methods to structure ligand and fragmentbased drug discovery
- Expert knowledge of the stateoftheart for computational chemistry and its application in drug discovery such as FEP and ML techniques
- Experience with commercial molecular modeling and data mining software
- Excellent oral and written communication skills
- Ability to multitask and set priorities on multiple projects
- Preferred Requirements
- Expertise with a wide array of computational methods preferably including structure and ligandbased virtual screening programming statistics data analysis QSAR derivation and application and ADME modeling
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Pay Range:
$123400 $185100Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other jobrelated factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive marketleading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a weeklong company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
HybridEligible Or OnSite EligibleFlex Eligibility Status:
In this HybridEligible role you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. OnSite: work five days per week onsite with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an EVerify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Required Experience:
Senior IC
Employment Type
Full-Time
