Postdoctoral Scientist
Postdoctoral Scientist
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Job Description
A twoyear postdoctoral scientist position (with the possibility of extension) is available at the James Hutton Institute funded by BBSRC sLola grant Exchanges at the haustorial interface: crosskingdom border control
This sLola project is an exciting collaboration linking key UK groups to investigate the molecular dialogue between Phytophthora pathogens and their plant hosts. It is an ambitious and technically challenging programme and this post requires a high level of expertise.
The JHI PDRA will become part of a team studying how Phytophthora secretes and delivers effector proteins into host cells. Tasks for this team will include endo and extracellular vesicle enrichment and immunopurification; identifying vesiclespecific regulatory and cargo proteins and their interactors and cocargo as well as apoplastic interactors associated with extracellular vesicle marker proteins MDP1/2; and investigation of how effectors are taken into plant cells via endocytosis The team will conduct cell biological analysis and imaging of coassociation of protein markers with RXLR effectors at vesicles and analysis of their potential roles in EV biogenesis. The team will also transform P. infestans to silence or knockout key trafficking regulators performing detailed cell biological and biochemical analyses on the transformants.
To ensure the project success we require a postdoctoral scientist with the following skills and experience:
Essential:
Broad molecular biology skills and experience
Excellent communication skills and an ability to work both independently and as part of a team
Proteomic sample preparation and analysis of data generated
High quality confocal microscopy
Confocal imaging of infected plant material
Experience with transformation of eukaryotic cells
Desirable:
Proximity labelling proteomics
Isolation and purification of extracellular vesicles
Transformation of Phytophthora species
Electron microscopy
Superresolution microscopy
Experience in gene silencing and editing
The appointee must also have the ability/capacity to spend time working in partner laboratories (Cambridge and Imperial) to ensure the exchanges of methods training and experience that are integral components of the project.
What we Offer
Employee Assistance Programme (EAP) A confidential service available to support employees and their families with work or personal problems. Providing access to professional counsellors psychologists and worklife consultants available to help and support individuals in tackling all types of problems.
Annual Leave Generous entitlement up to 40.5 days a year with carry over possible and guaranteed timeoff for Christmas.
Pension Employer Contribution of 15% in a Personal Pension Plan and employee contribution flexibility.
Selfmanaged hours and Flexible Working option to manage and spread your working time in line with organisational needs to create a healthy work life balance.
Additional Notes
- Please note the minimum salary threshold for a Skilled Worker Visa is currently 38700.00. If the advertised salary for this posts falls below this threshold we regret to advise that we may not be able to provide a Certificate of Sponsorship to a nonUK citizen for this role. Applicantswho do not meet the conditions to be sponsored as per the UK governments page ( will need to demonstrate an alternative right to work.
Our Commitment to Equality and Diversity
We will not consider the use of 3rd party recruitment agencies for the sourcing of candidates for this position.
The James Hutton Institute is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
The James Hutton Institute is a: Stonewall Diversity Champion; Athena SWAN Silver Status Holder; Disability Confident Committed Employer and a Living Wage Employer.
The James Hutton Institute is Happy to Talk Flexible Working.
The Company
The James Hutton Institute combines strengths in crops soils and land use and environmental research and makes a major contribution to the understanding of key global issues such as food energy and environmental security and developing and promoting effective technological and management solutions to these.
JamesHutton() was a leading figure of the Scottish Enlightenment an eighteenth century golden age of intellectual and scientific achievements centred on Edinburgh. He is internationally regarded as the founder of modern geology and one of the first scientists to describe the Earth as a living system. His thinking on natural selection influenced Charles Darwin in developing his theory of evolution.
Our Values
Documents
Employment Type
Temp
