Senior Scientist In Vitro ADME
Senior Scientist In Vitro ADME
Posted on :
28-04-2025
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1 Vacancy
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Job Description
Job Description Summary
As an ADME Scientist with Biomedical PK Sciences (PKS) organization you will facilitate the in vitro characterization of the drugdrug interaction (DDI) potential of drug candidates. The anticipation of the drugdrug interaction liabilities during the drug development process is critical in the context of understanding the safety and efficacy profile of the new drug candidate.The Drug Disposition (DD) group within PKS is seeking a highly qualified multidisciplinary teamoriented scientist having cell biology experience with emphasis on in vitro enzyme kinetics and ADME assays. In addition a strong background in bioanalytical methods including LC/MS radiochromatography and PCR is desirable. In this role the ADME scientist will elucidate drug metabolizing enzymes involved in the elimination of new drug candidates perform enzyme kinetics studies and determine the potential to inhibit or induce drug metabolizing enzymes. The responsibilities include researching new technologies in 3D cell culture models automation and bioanalytics to enhance the existing assay portfolio.
Job Description
Requirements:
- BS MS or PhD in biology biochemistry analytical chemistry or related disciplines.
- A good understanding of laboratory equipment particularly LC/MS
- Experience with handing of radioactive material and radio chromatography
- Proficiency in cell culture work and cellbased assays
- Experience with lab automation systems is desirable
- Demonstration of strong experimental and problemsolving skills excellent collaboration and communication skills (both written and oral) eagerness to learn and excellent time management skills are favored
- The ability to work in a teambased drug discovery/development environment is essential
Skills Desired
Required Experience:
Senior IC
Employment Type
Full-Time
Key Skills
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