Job Summary
Seeking highly motivated research scientist to perform mechanistic studies for the characterization of inflammatory and cell death pathways involved in the initiation and progression of solid tumors. PI Mei Kohs lab focuses on the identification of new therapeutic strategies that exploit the inflammatory and hypoxic tumor microenvironment. While some degree of freedom is expected the candidate will be expected to independently drive a research project which could include characterizing the role of the novel HAF NFB pathway in the initiation and progression of hepatocellular carcinoma HCC identifying novel pathways related to iron metabolism in kidney cancer and performing high throughput screens to identify novel small molecules with anticancer activity. Thus expertise in cell signaling pathways particularly those implicated in cancer is highly desirable. The candidate should also be able to write research articles and mentor lab technicians and graduate students with minimal supervision. Candidates must possess a PhD degree in biology biochemistry molecular pharmacology or related field. Candidates should have high proficiency in general cell biology and molecular biology techniques including cell culture molecular cloning western blots PCR and cell viability/reporter assays. Experience in animal handling/surgery is desirable but not essential. Candidates should be organized able to work independently and as part of a team in a highly collaborative research environment. Fluency in English is required. Candidates should be eligible to work in the USA .
Responsibilities
Responsibilities include: 1 Perform laboratory experiments which may include cell culture molecular cloning western blotting PCR small molecule screening animal handling/surgery and protein purification. 2 Plan and execute experiments perform data analysis have ability to work independently and as part of a team. 3 Present data in group meetings and at local and international meetings. 4 Supervise lab technicians and students. 5 Prepare manuscripts. The University of Utah and the Huntsman Cancer Institute: Founded in 1850 The University of Utah (the U) is the flagship institution of higher learning in Utah and offers over 100 undergraduate and more than 90 graduate degree programs to over 30000 students. As a preeminent research and teaching institution the University ranks among the top 50 U.S. universities by total research expenditures. Huntsman Cancer Institute HCI at the University of Utah is a nationally recognized research center and treatment hospital and an NCI designated Comprehensive Cancer Center. HCI and the U are located in Salt Lake City a vibrant increasingly diverse and family friendly city; nestled against the mountains of the Wasatch Front which provide world class skiing hiking biking and other alpine activities. This job description is not designed to contain or be interpreted as a comprehensive inventory of all duties responsibilities and qualifications required of employees assigned to the job. Work Environment and Level of Frequency that may be required Nearly Continuously: Office environment. Physical Requirements and Level of Frequency that may be required Nearly Continuously: Sitting hearing listening talking. Often: Repetitive hand motion (such as typing) walking. Seldom: Bending reaching overhead.
Minimum Qualifications
Bachelors degree in biology chemistry or other scientific discipline in a related field plus four years of experience or equivalency (one year of education can be substituted for two years of related work experience) required. Demonstrated human relations and effective communication skills also required. Applicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description.