At smartbax we aim to introduce the next generation of antibiotics. We develop novel antibacterial compounds with extraordinary potency against multi-drug resistant bacteria and hijack bacterial pathways that no other drug has touched before. As a start-up in Munichs vibrant biotech scene we offer an environment where your work makes a real difference. Help us pioneer new therapies that will save lives.
We are looking for a Senior Scientist (PhD) with expertise in structural biology and data science full-time starting immediately to join our growing team.
Tasks
- Structure-guided optimisation of small molecule antibiotic candidates through both in silico and experimental analyses
- Docking and molecular modelling studies to inform medicinal chemistry decision making
- Co-crystallization experiments with test compounds and target enzymes
- Coordination with CROs
- Implementation of AI and machine learning approaches for data analysis compound design and property prediction
- Data evaluation visualisation and presentation towards the team shareholders and investors
- Creative and critical thinking in solving scientific problems
Requirements
- PhD in structural biology computational chemistry or related subjects
- Experience in working with proteins and analysing small molecule-protein interactions
- Strong computational and programming skills including docking molecular dynamics machine learning and AI
- Additional expertise in handling S2 bacteria is considered a plus
- Self-organised enjoys working in small teams
- Creative fast-thinking and decisive mind who likes tackling challenges
- Proficient in written and spoken English; German skills are a plus
Benefits
- Purpose: Contribute to the fight against antimicrobial resistance one of the greatest healthcare challenges of our time
- Freedom and agility: Flat hierarchy fast decision making and no unnecessary bureaucracy allowing you to focus on things that really matter
- Shaping the companys future: Responsible position with direct impact and room for creativity in a highly motivated and experienced team
- A workplace tailored to your needs: 40 hours per week with flexible start and end times brand-new lab and office spaces and the freedom to work from home when needed
- Attractive benefits: Monthly vouchers for personal use (e.g. groceries wellness etc)
- Step into the future of biotech: Join a cutting-edge biotech start-up in Munich driving innovative drug development with strong venture capital support
Start: Immediately Location: Munich/Neuherberg (Life Science Factory at the Helmholtz Pioneer Campus)
Interested to join the smartbax team We look forward to receiving your application with a short cover letter CV and availability.