Job Summary
The Venosa Laboratory is seeking a highly motivated postdoctoral fellow to join our laboratorys NIEHS funded efforts to study the interplay between resident and infiltrating immune cells in the pathogenesis progression and resolution of lung inflammation in the healthy and functionally impaired lung. As the main platform to study susceptibility our group adopts a murine model of inflammatory exacerbations of pulmonary fibrosis triggered by aberrant expression of a clinically relevant mutant of the surfactant protein C gene candidates will independently lead projects in the above mentioned areas of emphasis. However flexibility on the specific project to be developed will be based on individual expertise and scientific interest. Active areas of research include: 1 identification of longlived myeloid and lymphoid populations central in coordinating tissue remodeling during all phases of mutant SPC induced exacerbation of pulmonary fibrosis; 2 phenotyping of macrophages eosinophils and B cell subsets during air pollution exposure in the healthy susceptible and fibrotic lung; and 3 modeling the impact of aging inflammatory cell function. Within the University of Utah the candidate will have access to stateoftheart core facilities in transcriptomics epigenomics proteomics and lipidomics and a highly engaging environment that encourages collaborations between toxicologists biologists and physician scientists from the pulmonary and geriatric divisions.