Position Summary
The laboratory of Dr. Terry Furey PhD in the Department of Genetics seeks a post-doctoral fellow to participate in his inflammatory bowel diseases ( IBD )-focused computational genomics research program part of a collaboration with Dr. Shehzad Shiekh MD PhD faculty in the Division of Gastroenterology and Hepatology. Dr. Furey and Dr. Sheikh collaborators for over 10 years aim to uncover the mechanistic linkages between the genome ( DNA sequence variants) epigenome (chromatin accessibility histone modifications) and the environment (metabolome intestinal microbiome) in the onset and progression of the complex diseases. We have performed multiple functional genomics experiments ( ATAC -seq RNA -seq scRNA-seq Cut-N-Run ChIP-seq miRNA-seq metabolomics) in tissue samples and individual cell types from colons and ileums of genotyped adult and pediatric IBD patients and controls. We are looking for a post-doctoral fellow to lead the computational analysis and interpretation of these data to further understand the molecular basis of this particular the candidate will lead our investigations into chromatin epigenetic and transcriptional alterations associated with disease phenotypes. The successful candidate will gain experience in several cutting-edge computational genomics analyses techniques and gain knowledge and expertise in diagnosis and treatment of IBD . Importantly these projects have great potential to become independent research projects that would further ambitious motivated post-doctoral addition to research the post-doctoral fellow will be actively involved with writing scientific papers and presenting talks at scientific meetings. There is also an opportunity to be involved in experiments in the Sheikh lab.
Required Qualifications Competencies And Experience
Experience in computational biology research
Preferred Qualifications Competencies And Experience
Candidates applying should be proficient in one or more of the following programming languages: Python Perl R Java C. Candidates must be familiar with the functional genomics experiments indicated above and have experience analyzing data from these experiments using robust computational mathematical and computational techniques. Experience leading and conducting these genomics experiments and performing research in inflammatory bowel diseases intestinal or immune-related diseases is highly desired. Candidates should have strong communication and analytical skills.
Required Experience:
IC