Postdoctoral Associate in cryogenic electron microscopy CryoEM
Postdoctoral Associate in cryogenic electron microscopy CryoEM
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Job Description
Postdoctoral Associate positions are immediately available in Professor Tina Izards cell adhesion laboratory.
The laboratory collaborates with several other laboratories on campus including exciting collaborative and currently active projects with Professors Kirill Martenmyanov Kendall Nettles https://doi/10.1073/ Valente Luiz Carvalho there are several exciting opportunities for a variety of very interesting projects beyondstructurefunction studies of cytoskeletal proteins that control signaling downstream of adherens junctions and focal adhesions with implications in cancer and heart diseasesand more recentlystructurefunction studies of novel Mycobacterium tuberculosis targets in collaboration with Professor Luiz Carvalho laboratory is recognized as a world leader and provides outstanding training in protein biochemistry and structural molecular and cellular biology in a highly dynamic and teamoriented research program.
Successful candidates will work in a cuttingedge research environment with new stateoftheart facilities. The laboratory has outstanding facilities for cell biology molecular biology protein expression purification and biochemistry and cryogenic electron microscopy and protein crystallography. The laboratory has access to a large cast of outstanding Cores that facilitate basic research and drug development. The unique infrastructure includes the application of unique chemical genomic proteomic informatics and highthroughput screening and engineering tools for the discovery of novel biomolecules.
Professor Tina Izard is a board member of the South East Regional Collaborative Access Team (SERCAT) that constructed two beam lines at the Advanced Photon Source (APS) at Argonne National Laboratory. The insertion device and bending magnet beam lines are available for all the synchrotronrelated data collection needs for the postdoctoral associates.
Professor Tina Izard recently installed the first 300 kV cryo Atomic Resolution Microscope (cryoARM300 in the Americas and has plenty of microscope time dedicated to the postdoctoral associate. This stateoftheart transmission electron microscope is a 300 kV high resolution microscope capable of carrying out cryogenicelectron microscopy studies by providing atomic resolution for structural studies involving single particle analyses. The transmission electron microscope is equipped with new and improved Gatan K3 direct electron detector camera that has better DQE larger field of view 24 Megapixels 5760 x 4092 and faster 3.75 times that of K2 camera). The direct detection devices are exquisitely sensitive produce high signal to noise images and are ideal for highresolution studies.
Professor Izard designed and installed a HighFlux Xray diffraction system specifically a Rigaku MicroMax007 HF a secondgeneration microfocus rotating anode generator together with a mar345 Image Plate detector. An Osmic VariMax optics system and the Proteros Free Mounting System can be used to control the humidity and to optimize diffraction characteristics including resolution mosaicity and anisotropy as well as reduced Xray background.
Commensurate with experience.
Applicants with a recently awarded Ph.D. degree in a relevant scientific discipline.
- Experience in cryogenic electron microscopy (cryoEM).
- Any structural biologist is highly encouraged to apply.
In order to be considered please upload CV cover letter or brief summary of research experience and interests and names addresses email and telephone numbers of 3 references.
This position has been reposted. Previous applicants are still under consideration and need not reapply.
For any inquiries you may contact Dr. T. Izard at
Cell Adhesion Laboratory
The final candidate will be required to provide official transcript to the hiring department upon hire. A transcript will not be considered official if a designation of Issued to Student is visible. Degrees earned from an education institution outside of the United States are required to be evaluated by a professional credentialing service provider approved by National Association of Credential Evaluation Services (NACES) which can be found athttp:// provide names and email addresses of three to five references as part of the UF application process. When ready the hiring department will contact the listed references via email requesting their reference letters to be uploaded directly to the application website.
This position is open until filled. Application review will begin January 19 2024.
This is a timelimited position.
Required Experience:
IC
Employment Type
Full Time
