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Title: Postdoctoral Fellow
Salary: $73 588
Department: Oncological Sciences
Physical work location: 1425 Madison Ave 15th floor New York NY 10029
Name PI or Supervisor: Triparna Sen Phd Associate Professor
1425 Madison Ave Office 1570E
New York New York 10029.
Web link to Lab: Contact: Evelyn Markov
The research study focuses on functional genomics and mouse models to understand the consequences of genetic and epigenetic alterations in lung cancer.
Technical Duties: (include any protocols)
You will participate in research to achieve a systematic and comprehensive understanding of the mechanisms of DNA repair DNA damage responses phenotypic plasticity immune regulatory pathways and immune escape mechanisms in human malignancies with a primary focus on lung cancer. You will employin vitroandin vivomodels of lung cancer multiple highthroughput screening technologies genomics proteomics CRISPR engineering and clinical samples to assess DNA repair DNA damage responses and immune sensing pathways and evaluate their effects on therapeutic response. You will apply advanced molecular assays including CRISPR screening immunological analysis pharmacological evaluations singlecell RNAseq and/or spatial transcriptomics to provide critical insights into the molecular circuitry that drives lung cancers and consequently results in the development of novel therapeutic strategies for the clinically relevant molecular subsets of lung cancer. You are expected to be on duty for approximately 37.5 hours per week.
Educational and other Requirements for the position: PhD
Experience Required: yes
824 Oncological Sciences ISM Icahn School of Medicine
Full-Time