Faculty Position in Neurotherapeutic Research

The Mayo Clinic Department of Neuroscience is recruiting an outstanding early to midcareer scientist (PhD MD/PhD MD or equivalent) with neurotherapeutic research focus and expertise in biotechnology and complex neurologic diseases including neurodegenerative dementias movement neurovascular neuroimmune disorders and aging. This individual is expected to establish a robust research program utilizing molecular therapeutic tools to develop therapeutic interventions for neurodegenerative and other complex neurologic disease processes and to take full advantage of the Center for Regenerative Biotherapeutics Mayo Clinic Innovation Exchange and Department of Neuroscience research programs at Mayo Clinic.

Candidates are expected to develop a robust nucleotide small molecule genetherapy and/or other modalitiesbased therapeutic programs. They would provide resources and establish platforms including but not limited to therapeutic design screening and applications to support existing neuroscience programs for the development of novel therapeutic interventions. In addition to supporting and collaborating with research scientists within the Neuroscience department the candidate is expected to establish an independent extramurally funded research program. Finally the candidate is expected to participate in education and institutional administrative activities. Current or prior experience in Industry or Biotechnology is preferred.

THE DEPARTMENT OF NEUROSCIENCE is internationally recognized for academic excellence with a specific focus on understanding the etiology and developing diagnostic and treatment methods for complex neurologic diseases including neurodegenerative dementias movement neurovascular neuroimmune disorders and aging. The Department spans all Mayo Clinic sites and includes 28 primary faculty members 62 allied health staff 126 postdoctoral associates and 36 doctoral students. Scientists within the neuroscience department have strong expertise in neurogenomics neuropathology disease modeling molecular and cell biology immunity and experimental therapeutics. The Department faculty play key roles in the Alzheimers Disease Research Center and other largescale NIHfunded consortia. In 2023 the Department of Neuroscience received over $50M in funding majority of which was from federal grants. Our faculty holds leadership roles on major NIH and foundation programs including but not limited to AMPAD CLEARAD Dementia with Lewy Bodies Consortium Tau Center without walls.

Breakthrough innovation does not just occur on its own. It requires focus hard work and being connected to the right people places and resources to make it all happen. The Mayo Clinic Innovation Exchange is a platform that supports all these needs bringing health care entrepreneurs startups and industry experts together to bring breakthrough innovations to market. Currently the Mayo Clinic Innovation Exchange supports over 90 startups all for one shared missionto benefit patients.

Highlights of Mayo Clinic Research Enterprise:

• Over 5000 research personnel including 317 faculty level research investigators and 909 physicians who are actively involved in research.
• 10505 peerreviewed papers were published in 2023.
• Investments in research each year that result in hundreds of new clinical trials. In 2023 the institution received over $689 million in extramural research awards supplemented with over $446 million of institutional support.
• Nearly 10000 active studies involving human participants in progress. More than 6050 research grants and contracts.
• Stateofthe art laboratories and shared resource facilities including those for microscopy and imaging cell and molecular biology animal models production of iPS cells and clinical grade MSCs biomedical engineering and mathematics materials testing a Medical Genomics Facility a Mouse Modeling Facility Molecular and Microscopic Core Facilities and unique Human Disease Tissue Banks.
• Over 420000 square feet of research laboratory space includes several robotic freezers capable of storing 3.5 million DNA samples.
• Mayo Clinic supports innovation and has a wealth of resources available including an integrated health record and collaboration with top specialists.
• Mayo Clinic Brain Bank housed within the Department of Neuroscience and including 11000 unique brains with neuropathologic characterizations from donors with neurodegenerative diseases and other conditions.

About Mayo Clinic

Mayo Clinic is top ranked in more specialties than any other care provider according to U.S. News & World Report. With a 73000person workforce Mayo Clinic cares for more than 1.3 million people each year with serious or complex illnesses from all 50 U.S. states and 130 countries. Mayo Clinic is the largest notforprofit multidisciplinary academic medical center in the world with over 4000 physicians and scientists in an integrated multicampus system spanning the globe.

The unified mission at Mayo Clinic is to provide the best patient care backed by our expertise and supported by innovation in education research and practice to bring hope and healing in times of need. We embrace collegial relationships among campuses (Arizona Florida and Minnesota) allowing for best practices and innovation to help solve the most serious complex medical challengesone patient at a time.

As we work together to put the needs of the patient first we are also dedicated to our employees investing in a highly competitive compensation package with substantial longterm institutional and departmental support for salary personnel equipment and travel as well as a competitive startup package all designed to ensure immediate and continued success. Additional benefits for faculty at Mayo Clinic include intramural funding opportunities for research and provide anoutstanding comprehensive benefits packagethat includes plenty of options for medical dental and vision care; flexible spending accounts; life insurance; short and longterm disability coverage; travel allowance; generous time away; and more! We are proud to be among the few U.S. companies to provide a pension benefit at no cost to employees plus you can add the Mayo 403(b) plan which features an employer match.