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Synthetic Biology - Postdoctoral Researcher

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Job Location drjobs

Livermore, CA - USA

Monthly Salary drjobs

Not Disclosed

drjobs

Salary Not Disclosed

Vacancy

1 Vacancy

Job Description

NOTE: This is a twoyear Postdoctoral appointment with the possibility of extension to a maximum of three years.

We are seeking a dedicated and hardworking postdoctoral researcher to conduct research in the field of synthetic biology for biocontainment of genetically modified microorganisms.  You will actively participate in research to develop biocontainment circuits in environmentally relevant bacteria and build and screen libraries for protein redesign. This position is in the Microbial systems or Synthetic biology group in the Biosciences and Biotechnology Division.

You will

  • Conduct fundamental research in microbial synthetic biology.
  • Employ state of the art library geneneration and develop high throughput approaches to assay the functionality of protein variants and microbial fitness.
  • Employ synthetic biology to implement biological circuits in environmental microorganisms and characterize efficacy in test beds of increasing complexity.
  • Engineer microbial communities for robust function.
  • Develop research plans generate results and publish peerreviewed papers.
  • Work with other scientists to write proposals and expand our program into new areas aligned with your expertise and interests.
  • Write reports to funding agencies and participate in scientific conferences.
  • Pursue independent (but complementary) research interests and interact with a broad spectrum of scientists internally and externally to the Laboratory.
  • Publish research results in peerreviewed scientific or technical journals and present results at external conferences seminars and/or technical meeting.
  • Perform other duties as assigned.

Qualifications :

  • The 2025 National Defense Authorization Act (NDAA) Section 3112 generally prohibits citizens of China Russia Iran and North Korea without dual US citizenship or legal permanent residence from accessing specific nonpublic areas of national security or nuclear weapons facilities.  The restrictions of NDAA Section 3112 apply to this position.  To be qualified for this position Candidates must be eligible to access the Laboratory in compliance with Section 3112.
  • PhD in Biological Sciences Bioengineering or a relevant field with a strong emphasis in synthetic biology and microbiology.
  • Expertise and knowledge in bacterial genetics and physiology
  • Experience in engineering bacterial strains for environmental function. This might include design assembly and modeling of genetic circuits.
  • Experience with high throughput screening/selection methods
  • Ability to develop independent research projects as demonstrated through publication of peerreviewed literature.
  • Proficient verbal and written communication and interpersonal skills to collaborate effectively in a multidisciplinary team environment and present and explain technical information.

Qualifications We Desire

  • Experience with microbial evolution approaches (e.g. adaptive laboratory evolution)
  • Experience with nextgeneration sequencing (NGS) and/or analysis
  • Experience with in silico protein design/engineering and/or directed experimental evolution of proteins
  • Experience with gene editing in nonmodel strains (nonE. coli systems).
  • Experience with bacterial signaling systems (e.g. two component systems quorum sensing systems)
  • Experience with synthetic microbial communities for bioproduction or environmental application
  • Experience in bioinformatics and/or proficiency in programming in one or more of the following languages: Python Julia C C R Java or Matlab


Additional Information :

All your information will be kept confidential according to EEO guidelines.

Position Information

This is a Postdoctoral appointment with the possibility of extension to a maximum of three years open to those who have been awarded a PhD at time of hire date.

Why Lawrence Livermore National Laboratory

Employment Type

Full-time

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