Head of Characterization

For over 25 years Abcam has been providing tools the scientific community needs to enable faster breakthroughs in critical areas like cancer neurological disorders infectious diseases and metabolic disorders.

We believe that to continue making progress we need to work together each bringing our own unique perspectives to make an impact on the world. This community needs people like you: dedicated agile and above all audacious so we can truly drive science forward.

The Head of Antibody Characterization is an R&D management role which will enable antibody and assay portfolio expansion by leading key stages of our antibody discovery and development workflow applying diverse screening techniques for high throughput antibody and antibody characterization. This role will manage and lead an antibody characterization team at our Waltham MA site and will collaborate closely with other functions such as antibody discovery protein sciences and assay development. We are looking for a leader with deep technical expertise in antibody and/or immunoassay development and strong organizational interpersonal verbal and written communication skills.

This position reports to Sr. Director Assays and North America R&D will be located in Waltham MA and will be based onsite and benchfacing. At Abcam our vision is to be the most influential life sciences company for researchers worldwide.

In this role you will have the opportunity to:

• Establish and lead a highperforming antibody characterization team manage a team of direct reports and provide leadership guidance and mentorship to ensure project goals are met effectively and on time.
• Determine antibody purity and function using SDSPAGE WB SEC ELISA SPR and other immunoscreening assays.
• Perform and/or manage multiple highthroughput antibody screening assays such as binding kinetics ligand blocking and epitope binning to rapidly identify lead candidates.
• Design and develop assays for the identification and characterization of antibody pairs for use in sandwich immunoassay platforms partnering close with internal and external stakeholders to determine optimal screening and selection criteria.
• Manage a cell sciences team and ensure that appropriate biospecimens are always on hand for evaluation of antibody performance and specificity.
• Design execute and troubleshoot diverse assays analyze complex data and routinely present findings during crossfunctional team meetings.
• Stay current with antibody discovery biology and advancements in technologies to improve the performance and throughput of antibody screening and characterization assays.

The essential requirements of the job include:

• Advanced degree in biology/biochemistry/related field or equivalent work experience with 8 years experience of responsibility for developing antibodies or immunoassays at least 5 years management experiences.
• Expertise and hand on experiences in IHC ChIP ELISA IF/ICC flow cytometry western blot etc.
• Strong leadership skills ideally with prior experience of effectively managing reports influencing crossfunctionally training new hires and fostering a collaborative work environment.
• Extensive experience with designing and conducting in vitro proteinbased assays using a variety of biochemical & enzyme kinetics assays for antibody characterization.
• Experience and domain expertise with diverse assay types such as Western Blot ELISA SPR HTRF AlphaLisa Flow Cytometry etc.
• High degree of data literacy for example with antibody screening databases data analysis/visualization software and statistical analysis of data..

Travel Motor Vehicle Record & Physical/Environment Requirements:

• Ability to lift move or carry equipment up to 50lb (not routinely).
• This role is partially labbased and may involve standing for over 50 of the time.

It would be a plus if you also possess previous experience in:

• Capacity planning / resource allocation/ project timeline management.
• General management experience including managing budgets reporting performance actively managing employee performance and development.
• Expertise with programming and/or operating automated laboratory equipment.

The salary range OR the hourly range for this role is $120000 $150000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future.

This job is also eligible for bonus/incentive pay.

We offer comprehensive package of benefits including paid time off medical/dental/vision insurance and 401(k) to eligible employees.

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Join our winning team today. Together well accelerate the reallife impact of tomorrows science and technology. We partner with customers across the globe to help them solve their most complex challenges architecting solutions that bring the power of science to life.

For more information visit www.danaher.

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We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform crucial job functions and to receive other benefits and privileges of employment. Please contact us at to request accommodation.